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首页 > 抗体蛋白 > 抗体
PerCP/Cyanine5.5 anti-mouse CD103 Antibody
产品名称：
PerCP/Cyanine5.5 anti-mouse CD103 Antibody
产品类别：
抗体
产品编号：
121415
产品应用：
121415
[价格]
规格 价格 库存
25µg ￥ 1692 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse intestinal intraepithelial lymphocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemical staining1,7 of acetone-fixed frozen sections, immunofluorescence2, and in vitro activation1.

Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. LeFrancois L, et. al, 1994. Eur. J. Immunol. 24:635. (FC, IHC, IP)
  2. Mysorekar IU, et. al, 2002. J. Biol. Chem. 277:37811. (FC, IF)
  3. Mikami N, et al. 2011. J. Immunol. 186:6886. PubMed
  4. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
  5. Quinn KM, et al. 2013. J. Immunol. 191:5085. PubMed
  6. Verhagen J and Wraith DC. 2014. J. Immunol. Methods. S0022. (FC) PubMed
  7. Xiao B, et al. 2015. PLoS One 1:e0115333. (IHC)
Product Citations
  1. Quinn K, et al. 2013. J Immunol. 191:5085. PubMed
  2. Ender F, et al. 2017. PLoS One. 12(2):e0172446. PubMed
  3. Ritzel R, et al. 2016. J Immunol. 196: 3318-3330. PubMed
  4. Verhagen J, et al. 2013. PLoS One. 8:61334. PubMed
  5. Wang D, et al. 2018. Immunity. 48:659. PubMed
  6. Sauter M, et al. 2022. iScience. 25:103677. PubMed
  7. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  8. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  9. Wiese A, et al. 2017. PLoS One. 10.1371/journal.pone.0184956. PubMed
  10. Kitano M, et al. 2016. Proc Natl Acad Sci U S A. 113: 1044 - 1049. PubMed
  11. Karsten C, et al. 2015. J Immunol. 194:1841. PubMed
  12. Blijswijk J, et al. 2015. J Immunol. 194:307. PubMed
  13. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  14. Kinsella S, et al. 2021. Cell Rep. 37:109789. PubMed
  15. Cuburu N, et al. 2019. J Immunol. 202:1250. PubMed
  16. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  17. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  18. Boucard-Jourdin M, et al. 2016. J Immunol. 197: 1968 - 1978. PubMed
  19. Port JR, et al. 2020. J Virol. 94:. PubMed
  20. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  21. Huang S, et al. 2016. Immunol Cell Biol. 10.1038/icb.2016.75. PubMed
  22. Giampazolias E, et al. 2021. Cell. . PubMed
  23. Hoffmann FM, et al. 2018. Front Immunol. 9:1046. PubMed
  24. Kelly SH, et al. 2021. ACS Biomater Sci Eng. 7:1876. PubMed
  25. Luck H, et al. 2019. Nat Commun. 10:3650. PubMed
  26. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  27. Penke LR, et al. 2020. Life Sci Alliance. 3:. PubMed
  28. Yasuda T, et al. 2016. PLoS One. 11:e0167952. PubMed
  29. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  30. Meunier I, et al. 2015. PLoS One. 10: 0138055. PubMed
  31. Reed HO, et al. 2019. J Clin Invest. 130:2514. PubMed
  32. Pavelko K, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01532. PubMed
  33. Gaylo‐Moynihan A et al. 2019. Immunity. 51(2):298-309 . PubMed
  34. Kautz-Neu K, et al. 2011. J Exp Med. 208:885. PubMed
  35. Ubags ND, et al. 2021. J Allergy Clin Immunol. 1049:147. PubMed
  36. Sheng J, et al. 2021. eLife. 10:00. PubMed
  37. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  38. Lian M, et al. 2015. PLoS One. 10: 0132741. PubMed
  39. Waaler J, et al. 2020. Commun Biol. 3:196. PubMed
  40. Chen R, et al. 2021. Front Oncol. 11:743050. PubMed
  41. Spath S, et al. 2022. iScience. 25:104998. PubMed
RRID
AB_1574957 (BioLegend Cat. No. 121415) AB_2128621 (BioLegend Cat. No. 121416)

Antigen Details

Structure
Type I transmembrane glycoprotein, Integrin family, can be cleaved into 150 kD and 25 kD chains, associated with β7 integrin
Distribution

Majority of intestinal intraepithelial lymphocytes (IEL), subpopulation of lamina propria T cells, epithelial dendritic cells, small subset of peripheral lymphocytes, Treg cells.

Function
Retention and activation of CD103+ lymphocytes in the intestinal epithelium, regulate tissue-specific T cell homing.
Ligand/Receptor
E-Cadherin
Cell Type
Dendritic cells, Lymphocytes, T cells, Tregs
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Kilshaw PJ and SJ. Murant. 1990. Eur. J. Immunol. 20:2201.
2. Karecla PI, et al. 1995. Eur. J. Immunol. 25:852.
3. LeFrancois L, et al. 1994. Eur. J. Immunol. 24:635.
4. Sung SS, et al. 2006. J. Immunol. 176:2161.
5. Johansson-Lindbom B, et al. 2005. J. Exp. Med. 202:1063.
6. Dujardin HC, et al. 2004. Proc. Natl. Acad. Sci. USA. 101:14473.

Gene ID
16407 View all products for this Gene ID
UniProt
View information about CD103 on UniProt.org

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