Purified anti-IDO1 Antibody
- 产品名称：
- Purified anti-IDO1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 654001
- 产品应用：
- 654001
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant mouse IDO1.
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- Protein G affinity purified.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone 2E2/IDO1 reacts with mouse IDO1. It does not appear to react with mouse IDO2.
- Product Citations
-
- Ji R, et al. 2021. PLoS One. 16:e0258204. PubMed
- Yuk H, et al. 2021. Antioxidants (Basel). 10:. PubMed
- Moritsch S, et al. 2022. Oncoimmunology. 11:2127271. PubMed
- RRID
- AB_2561779 (BioLegend Cat. No. 654001) AB_2561780 (BioLegend Cat. No. 654002)
- Structure
- 403 amino acids with a predicted molecular weight of 45 kD.
- Distribution
-
Cytoplasm
- Function
- Indoleamine 2,3-dioxygenase (IDO) is an IFN-γ inducible gene. It catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens.
- Interaction
- This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin.
- Biology Area
- Cell Biology, Immunology
- Antigen References
-
1. Habara-Ohkubo A, et al. 1991. Gene 105:221.
2. Munn DH, et al. 2002. Science 297:1867.
3. Frumento G, et al. 2002. J. Exp. Med. 196:459.
4. Muller AJ, et al. 2005. Nature Med. 11:312.
5. Lob S, et al. 2009. Nature Rev. Cancer 9:445.
- Gene ID
- 15930 View all products for this Gene ID
- UniProt
- View information about IDO1 on UniProt.org
