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PerCP anti-human CD45 Antibody
产品名称:
PerCP anti-human CD45 Antibody
产品类别:
抗体
产品编号:
368505
产品应用:
368505
[价格]
规格 价格 库存
25tests ¥ 1392 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human PBMC
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* PerCP has a maximum absorption of 482 nm and a maximum emission of 675 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.

Application References

(PubMed link indicates BioLegend citation)
  1. Bradstock KF, et al. 1980. J. Natl. Cancer Inst. 65:33.
  2. Csiba A, et al. 1984. Br. J. Cancer 50:699.
  3. Tchilian EZ, et al. 2001. J. Immunol. 166:1308.
  4. Lee MS, et al. 2004. Int. Immunol. 16:1109.
Product Citations
  1. Oostindie SC, et al. 2022. Nat Biotechnol. :. PubMed
  2. Kreutmair S, et al. 2021. Immunity. . PubMed
  3. Yang HL, et al. 2020. Am J Reprod Immunol. 84:e13261. PubMed
  4. Mulfaul K, et al. 2020. Cell Rep. 30:2209. PubMed
  5. Wu H, et al. 2022. Biomolecules. 12:. PubMed
  6. Fu J, et al. 2020. Curr Protoc Pharmacol. 89:e76. PubMed
  7. B?cker-Koduah P, et al. 2020. Ann Clin Transl Neurol. 1.422222222. PubMed
  8. Shen C, et al. 2021. Front Immunol. 12:680055. PubMed
  9. Sawasdee N, et al. 2022. Int J Mol Med. 49:. PubMed
  10. Lozano-Rodríguez R, et al. 2022. Cell Rep. 38:110235. PubMed
  11. Li X, et al. 2021. Hemodial Int. 25:489. PubMed
  12. Zhang Q, et al. 2021. Sci Transl Med. 13:eabg6986. PubMed
  13. Janssen JJE, et al. 2022. Am J Physiol Endocrinol Metab. 322:E141. PubMed
  14. Weiss R, et al. 2021. Cells. 10:. PubMed
  15. Hu BS, et al. 2020. Cancer Cell Int. 1.189583333. PubMed
  16. Panigrahi S, et al. 2020. Eur J Immunol. 50:2055. PubMed
  17. Baliu-Piqu M, et al. 2021. eLife. 10:00. PubMed
  18. Yu Y, et al. 2017. Stem Cell Reports. 10.1016/j.stemcr.2017.07.016. PubMed
  19. Deng P, et al. 2020. Bone Res. 8:39. PubMed
RRID
AB_2566357 (BioLegend Cat. No. 368505) AB_2566358 (BioLegend Cat. No. 368506)

Antigen Details

Structure
Type I transmembrane protein, 180 - 240 kD (multiple isoforms)
Distribution

Hematopoietic cells, except circulating erythrocytes or platelets.

Function
Tyrosine phosphatases, signaling, co-stimulation (co-inhibition), TCR and BCR mediated activation.
Ligand/Receptor
Galectin-1, CD2, CD3, and CD4.
Cell Type
B cells, Dendritic cells, Neutrophils
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules, Protein Kinases/Phosphatase, TCRs
Antigen References

1. Thomas M. 1989. Annu. Rev. Immunol. 7:339.
2. Trowbridge I, et al. 1994. Annu. Rev. Immunol. 12:85.

Gene ID
5788 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

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