FITC anti-human CD45 Antibody
- 产品名称：
- FITC anti-human CD45 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 368507
- 产品应用：
- 368507
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human PBMC
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.
- Application References
(PubMed link indicates BioLegend citation) -
- Bradstock KF, et al. 1980. J. Natl. Cancer Inst. 65:33.
- Csiba A, et al. 1984. Br. J. Cancer 50:699.
- Tchilian EZ, et al. 2001. J. Immunol. 166:1308.
- Lee MS, et al. 2004. Int. Immunol. 16:1109.
- Product Citations
-
- Xin Y, et al. 2021. Stem Cell Res Ther. 49:12. PubMed
- Liu X, et al. 2020. Exp Ther Med. 1.258333333. PubMed
- Radhakrishnan S, et al. 2019. Mol Med Rep. 20:813. PubMed
- Tu S, et al. 2020. Cellular Signalling. 73:109695. PubMed
- Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
- Wu S, et al. 2020. Stem Cells Int. 2019:1515040. PubMed
- Sun W, et al. 2019. Exp Ther Med. 17:2199. PubMed
- Hijmans JG, et al. 2019. J Am Heart Assoc. 8:e011134. PubMed
- Mehta AK, et al. 2021. Nat Cancer. 2:66. PubMed
- Bhattacharya M, et al. 2020. Infect Immun. :88. PubMed
- Shen C, et al. 2021. Front Immunol. 12:680055. PubMed
- Escudero–Pérez B, et al. 2019. JCI Insight. 4:e126070. PubMed
- Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
- Zhan L, et al. 2022. Cancer Lett. 529:37. PubMed
- Meng X, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
- Motedayyen H, et al. 2017. BMC Res Notes. . 10.1186/s13104-017-2880-6. PubMed
- He Z, et al. 2020. J Exp Clin Cancer Res. 39:140. PubMed
- Felker S, et al. 2022. JCI Insight. 7:. PubMed
- Gleitz HFE, et al. 2021. STAR Protocols. 2(2):100538. PubMed
- Lin T, et al. 2021. PLoS Pathog. 17:e1009557. PubMed
- Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
- Matsuo S, et al. 2021. PLoS One. e0247595:16. PubMed
- Togami K, et al. 2019. J Clin Invest. 129:5005. PubMed
- Hu Q, et al. 2021. Nat Biomed Eng. 5:1038. PubMed
- RRID
- AB_2566367 (BioLegend Cat. No. 368507) AB_2566368 (BioLegend Cat. No. 368508)
- Structure
- Type I transmembrane protein, 180 - 240 kD (multiple isoforms)
- Distribution
-
Hematopoietic cells, except circulating erythrocytes or platelets.
- Function
- Tyrosine phosphatases, signaling, co-stimulation (co-inhibition), TCR and BCR mediated activation.
- Ligand/Receptor
- Galectin-1, CD2, CD3, and CD4.
- Cell Type
- B cells, Dendritic cells, Neutrophils
- Biology Area
- Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules, Protein Kinases/Phosphatase, TCRs
- Antigen References
-
1. Thomas M. 1989. Annu. Rev. Immunol. 7:339.
2. Trowbridge I, et al. 1994. Annu. Rev. Immunol. 12:85.
- Gene ID
- 5788 View all products for this Gene ID
- UniProt
- View information about CD45 on UniProt.org
