APC/Cyanine7 anti-human CD45 Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD45 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 368515
- 产品应用：
- 368515
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1656 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human PBMC
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
It was found that the HI30 clone and the 2D1 clone can cross block each other's binding.
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Bradstock KF, et al. 1980. J. Natl. Cancer Inst. 65:33.
- Csiba A, et al. 1984. Br. J. Cancer 50:699.
- Tchilian EZ, et al. 2001. J. Immunol. 166:1308.
- Lee MS, et al. 2004. Int. Immunol. 16:1109.
- Product Citations
-
- Liu C, et al. 2021. Cell. 184(7):1836-1857.e22. PubMed
- Healy LM, et al. 2020. Glia. 68:811. PubMed
- Wang H, et al. 2022. Front Immunol. 13:852436. PubMed
- Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
- Merugu S, et al. 2020. Methods Enzymol. 639:289. PubMed
- Philippeos C, et al. 2018. J Invest Dermatol. 138:811. PubMed
- Kou R, et al. 2018. Oncol Rep. 7:2013. PubMed
- Srideshikan SM, et al. 2019. Clin Cancer Res. 25:7463. PubMed
- Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
- Dong Y, et al. 2020. J Leukoc Biol. 108:1711. PubMed
- Hasselmann J, et al. 2020. Neuron. 103(6):1016-1033. PubMed
- Jing Y, et al. 2020. Cancer Gene Ther. 27:910. PubMed
- Pandolfi J, et al. 2016. J Immunol. 196: 3287-3296. PubMed
- Hazenberg MD, et al. 2019. Blood Adv. 2.659722222. PubMed
- Shi X, et al. 2022. Clin Transl Med. 12:e711. PubMed
- Still C 2nd, et al. 2021. Cell Reports Medicine. 2(7):100343. PubMed
- Zhou WJ, et al. 2022. Sci Adv. 8:eabj2488. PubMed
- Voskamp C, et al. 2020. Front Bioeng Biotechnol. 0.790277778. PubMed
- Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
- Hoffmann J, et al. 2021. Nat Commun. 12:3964. PubMed
- Xi H, et al. 2020. Cell Stem Cell. 27(1):158-176. PubMed
- Zhou F, et al. 2018. Cancer Manag Res. 0.727083333. PubMed
- Hu J, et al. 2022. J Immunother Cancer. 10:. PubMed
- Ruan LY, et al. 2022. Biomolecules. 12:. PubMed
- Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
- Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed
- Dou D, et al. 2016. Nat Cell Biol. 18: 595-606. PubMed
- Karlsson J, et al. 2020. Nat Commun. 1.773611111. PubMed
- Antonyshyn JA, et al. 2021. Commun Biol. 4:1205. PubMed
- Tan EE, et al. 2020. J Clin Invest. 130:5817. PubMed
- RRID
- AB_2566375 (BioLegend Cat. No. 368515) AB_2566376 (BioLegend Cat. No. 368516)
- Structure
- Type I transmembrane protein, 180 - 240 kD (multiple isoforms)
- Distribution
-
Hematopoietic cells, except circulating erythrocytes or platelets.
- Function
- Tyrosine phosphatases, signaling, co-stimulation (co-inhibition), TCR and BCR mediated activation.
- Ligand/Receptor
- Galectin-1, CD2, CD3, and CD4.
- Cell Type
- B cells, Dendritic cells, Neutrophils
- Biology Area
- Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules, Protein Kinases/Phosphatase, TCRs
- Antigen References
-
1. Thomas M. 1989. Annu. Rev. Immunol. 7:339.
2. Trowbridge I, et al. 1994. Annu. Rev. Immunol. 12:85.
- Gene ID
- 5788 View all products for this Gene ID
- UniProt
- View information about CD45 on UniProt.org
