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APC anti-mouse/rat CD61 Antibody
产品名称:
APC anti-mouse/rat CD61 Antibody
产品类别:
抗体
产品编号:
104315
产品应用:
104315
[价格]
规格 价格 库存
25µg ¥ 1224 1

产品详情

Product Details

Verified Reactivity
Mouse, Rat
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 104325 and 104326).

Application References

(PubMed link indicates BioLegend citation)
  1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
  2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
  3. Ashkar S, et al. 2000. Science 287:860. (Block)
  4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
  5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
  6. Carlson TR, et al. 2008.135:2193. PubMed
  7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations
  1. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  2. Dignum T, et al. 2021. Cell Rep. 36:109675. PubMed
  3. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  4. Yamamoto M, et al. 2019. Commun Biol. 2:292. PubMed
  5. Pervolarakis N, et al. 2020. Cell Rep. 108273:33. PubMed
  6. Ni T, et al. 2016. Nat Cell Biol. 18:1221-1232. PubMed
  7. Lucotti S, et al. 2019. J Clin Invest. 130:1845. PubMed
RRID
AB_2561733 (BioLegend Cat. No. 104315) AB_2561734 (BioLegend Cat. No. 104316)

Antigen Details

Structure
Integrin family, 110 kD
Distribution

Platelets, megakaryocytes, endothelium, smooth muscle, activated T cells, subset of B cells, monocytes, macrophages, osteoclasts, mast cells

Function
Attachment to matrix
Ligand/Receptor
Fibrinogen, von Willebrand factor, fibronectin
Cell Type
B cells, Endothelial cells, Macrophages, Mast cells, Megakaryocytes, Monocytes, Osteoclasts, Platelets, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook. Academic Press.
2. Phillips DR, et al. 1991. Cell. 65:359.
3. Felding-Habermann B, et al. 1993. Curr?Opinion Cell Biol. 5:864.

Gene ID
16416 View all products for this Gene ID 29302 View all products for this Gene ID
UniProt
View information about CD61 on UniProt.org

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