Purified anti-human CX3CR1 Antibody
- 产品名称：
- Purified anti-human CX3CR1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 341602
- 产品应用：
- 341602
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CX3CR1-EGFP fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Nishimura M, et al. 2002. J. Immunol. 168:6173.
- Nanki T, et al. 2002. Arthritis Rheum. 46:2878.
- Kobayashi T, et al. 2007. Inflamm. Bowel Dis. 13:837.
- Beziat V, et al. 2011. J. Immunol. 186:6753. PubMed.
- Product Citations
-
- Panigrahi S, et al. 2020. PLoS Pathog. e1008885:16. PubMed
- Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Taft J, et al. 2021. Cell. 184(17):4447-4463.e20. PubMed
- Tian Y, et al. 2019. Cell Rep. 29:4482. PubMed
- Gruber CN, et al. 2020. Immunity. 53(3):672-684. PubMed
- Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
- Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
- Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed
- NULL, et al. 2022. Cell. 185:916. PubMed
- Béziat V, et al. 2011. J Immunol. 186:6753. PubMed
- RRID
- AB_1595422 (BioLegend Cat. No. 341602)
- Structure
- G-protein-coupled seven transmembrane receptor
- Distribution
-
NK cells, T cell subset, monocytes/macrophages, dendritic cells
- Function
- cell adhesion and migration
- Ligand/Receptor
- CX3CL1 (Fractalkine, FKN, neurotactin)
- Cell Type
- Dendritic cells, Macrophages, Monocytes, NK cells, T cells
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Imai T, et al. 1997. Cell. 91:521.
2. Fong AM, et al. 1998. J. Exp. Med. 188:1413.
3. Auffray C, et al. 2009. J. Exp. Med. 206:595.
- Gene ID
- 1524 View all products for this Gene ID
- UniProt
- View information about CX3CR1 on UniProt.org
