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PE anti-human CX3CR1 Antibody
产品名称:
PE anti-human CX3CR1 Antibody
产品类别:
抗体
产品编号:
341603
产品应用:
341603
[价格]
规格 价格 库存
25tests ¥ 1548 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
CX3CR1-EGFP fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Nishimura M, et al. 2002. J. Immunol. 168:6173.
  2. Nanki T, et al. 2002. Arthritis Rheum. 46:2878.
  3. Kobayashi T, et al. 2007. Inflamm. Bowel Dis. 13:837.
  4. Beziat V, et al. 2011. J. Immunol. 186:6753. PubMed.
Product Citations
  1. Cannon J, et al. 2014. Physiol Rep. 2:12177. PubMed
  2. Weiskopf D, et al. 2015. Proc Natl Acad Sci U S A. 112: E4256-E4263. PubMed
  3. Morandi F, et al. 2014. J Immunol. 192:2634. PubMed
  4. Lewis SA, et al. 2021. Front Immunol. 12:724015. PubMed
  5. Izmirly AM, et al. 2022. PLoS Pathog. 18:e1009903. PubMed
  6. Sureshchandra S, et al. 2021. iScience. 24:102690. PubMed
  7. Buggert M, et al. 2020. Cell. 183(7):1946-1961.e15. PubMed
  8. Fraccarollo D, et al. 2021. eLife. 0.416666666666667. PubMed
  9. Guttikonda SR, et al. 2021. Nat Neurosci. 24:343. PubMed
  10. Agace W, et al. 2014. J Leukoc Biol. 95:531. PubMed
  11. Leers M,et al. 2017. Cytometry A.. 10.1002/cyto.a.23263. PubMed
  12. Yin S, et al. 2015. Sci Rep. 5: 14432. PubMed
  13. Collins PL et al. 2018. Cell. 176(1-2):348-360 . PubMed
RRID
AB_1595552 (BioLegend Cat. No. 341603) AB_1595456 (BioLegend Cat. No. 341604)

Antigen Details

Structure
G-protein-coupled seven transmembrane receptor
Distribution

NK cells, T cell subset, monocytes/macrophages, dendritic cells

Function
cell adhesion and migration
Ligand/Receptor
CX3CL1 (Fractalkine, FKN, neurotactin)
Cell Type
Dendritic cells, Macrophages, Monocytes, NK cells, T cells
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Molecular Family
Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Imai T, et al. 1997. Cell. 91:521.
2. Fong AM, et al. 1998. J. Exp. Med. 188:1413.
3. Auffray C, et al. 2009. J. Exp. Med. 206:595.

Gene ID
1524 View all products for this Gene ID
UniProt
View information about CX3CR1 on UniProt.org

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