Biotin anti-human ROR1 Antibody
- 产品名称：
- Biotin anti-human ROR1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 357816
- 产品应用：
- 357816
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone 2A2 binds to the membrane distal Ig-domain of ROR1. Clone 2A2 has also been shown to exhibit cross reactivity towards mouse ROR12.
- Application References
(PubMed link indicates BioLegend citation) -
- Dave H, et al. 2012. PLoS One 7:e52655. (FC)
- Baskar S, et al. 2012. MAbs. 4:349. (FC)
- RRID
- AB_2715938 (BioLegend Cat. No. 357816)
- Structure
- Type I transmembrane protein, consist of 1 frizzled domain, 1 Ig-like C2-type domain, 1 kringle domain, and 1 non-functional kinase domain; member of the ROR subfamily of surface receptors
- Distribution
-
Embryonic tissue, central nervous system, chronic lymphocytic leukemia cells
- Ligand/Receptor
- Wnt5a
- Cell Type
- Embryonic Stem Cells, Leukemia
- Biology Area
- Immunology, Stem Cells
- Antigen References
-
- Bicocca VT, et al. 2012. Cancer Cell. 22:656.
- Zhang S, et al. 2012. PLoS One 7:e31127.
- Uhrmacher S, et al. 2011. Leuk Res. 35:1360.
- Yang J, et al. 2011. PLoS One 6:e21018.
- Grumolato L, et al. 2010. Genes Dev. 24:2517.
- Gene ID
- 4919 View all products for this Gene ID
- UniProt
- View information about ROR1 on UniProt.org
