APC anti-human ROR1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1932	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Red Laser (633 nm)

Application Notes

Clone 2A2 binds to the membrane distal Ig-domain of ROR1. Clone 2A2 has also been shown to exhibit cross reactivity towards mouse ROR1².

Application References (PubMed link indicates BioLegend citation)

Dave H, et al. 2012. PLoS One 7:e52655. (FC)
Baskar S, et al. 2012. MAbs. 4:349. (FC)

Product Citations

Ljungars A, et al. 2019. Front Pharmacol. 10:847. PubMed

RRID

AB_2562371 (BioLegend Cat. No. 357805) AB_2562372 (BioLegend Cat. No. 357806)

Antigen Details

Structure

Type I transmembrane protein, consist of 1 frizzled domain, 1 Ig-like C2-type domain, 1 kringle domain, and 1 non-functional kinase domain; member of the ROR subfamily of surface receptors

Distribution

Embryonic tissue, central nervous system, chronic lymphocytic leukemia cells

Ligand/Receptor

Wnt5a

Cell Type

Embryonic Stem Cells, Leukemia

Biology Area

Immunology, Stem Cells

Antigen References