PE/Cyanine7 anti-mouse CD196 (CCR6) Antibody
- 产品名称：
- PE/Cyanine7 anti-mouse CD196 (CCR6) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 129815
- 产品应用：
- 129815
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Product Citations
-
- Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
- Boccasavia VL, et al. 2021. Cell Reports. 34(11):108861. PubMed
- Withers D, et al. 2016. Nat Med. 22:319-23. PubMed
- Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
- Emg?rd J, et al. 2018. Immunity. 143:419. PubMed
- Marks KE, et al. 2021. Cell Reports. 35(13):109303. PubMed
- Zanvit P, et al. 2015. Nat Commun. 6: 8424. PubMed
- Suan D et al. 2017. Immunity. 47(6):1142-1153 . PubMed
- Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
- Nikolouli E, et al. 2020. Cell Mol Immunol. . PubMed
- Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
- RRID
- AB_1877244 (BioLegend Cat. No. 129815) AB_2072798 (BioLegend Cat. No. 129816)
- Structure
- G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6
- Distribution
-
Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset
- Function
- Important in regulating mucosal immune response
- Ligand/Receptor
- CCL20/MIP-3a
- Cell Type
- B cells, Dendritic cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Rossi D, et al. 1997. J. Immunol. 158:1033.
2. Lukacs N, et al. 2001. J. Exp. Med. 194:551.
3. Cook DN, et al. 2000. Immunity 12:495
- Gene ID
- 12458 View all products for this Gene ID
- UniProt
- View information about CD196 on UniProt.org
