Brilliant Violet 421™ anti-mouse CD196 (CCR6
- 产品名称：
- Brilliant Violet 421™ anti-mouse CD196 (CCR6
- 产品类别：
- 抗体
- 产品编号：
- 129817
- 产品应用：
- 129817
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Product Citations
-
- Cibrián D, et al. 2020. J Allergy Clin Immunol. 145:199. PubMed
- Kathania M, et al. 2016. Nat Immunol. 10.1038/ni.3488. PubMed
- Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
- Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
- Miyazaki M et al. 2017. Immunity. 46(5):818-834 . PubMed
- Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
- Grioni M, et al. 2021. Blood Adv. 5:2817. PubMed
- Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
- Kawabe T, et al. 2013. J Immunol. 190:5788. PubMed
- Guendel F, et al. 2020. Immunity. 53(5):1015-1032.e8. PubMed
- Seo GY et al. 2018. Cell host & microbe. 24(2):249-260 . PubMed
- Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
- Jaeger N, et al. 2020. Cell Rep. 33:108331. PubMed
- Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
- Wanke-Jellinek L, et al. 2016. J Leukoc Biol. 99: 483 - 493. PubMed
- RRID
- AB_10898320 (BioLegend Cat. No. 129817) AB_11219003 (BioLegend Cat. No. 129818)
- Structure
- G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6
- Distribution
-
Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset
- Function
- Important in regulating mucosal immune response
- Ligand/Receptor
- CCL20/MIP-3a
- Cell Type
- B cells, Dendritic cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Rossi D, et al. 1997. J. Immunol. 158:1033.
2. Lukacs N, et al. 2001. J. Exp. Med. 194:551.
3. Cook DN, et al. 2000. Immunity 12:495
- Gene ID
- 12458 View all products for this Gene ID
- UniProt
- View information about CD196 on UniProt.org
