APC anti-mouse CD196 (CCR6) Antibody
- 产品名称：
- APC anti-mouse CD196 (CCR6) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 129813
- 产品应用：
- 129813
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Wang X, et al. 2019. Cell Res. 29:787. PubMed
- Liu J, et al. 2011. PLoS One. 6:e19495. PubMed
- Sundling C, et al. 2021. Immunity. 54(5):988-1001.e5. PubMed
- Yan J, et al. 2020. Cell Rep. 107820:31. PubMed
- DiToro D, et al. 2020. Immunity. 650:52. PubMed
- Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
- Suan D et al. 2017. Immunity. 47(6):1142-1153 . PubMed
- Ulaganathan VK, et al. 2020. Sci Rep. 10:8453. PubMed
- Mony J, et al. 2014. Mult Scler. . PubMed
- Zhong C, et al. 2020. Immunity. 52(1):83-95.e4.. PubMed
- Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
- RRID
- AB_1877148 (BioLegend Cat. No. 129813) AB_1877147 (BioLegend Cat. No. 129814)
- Structure
- G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6
- Distribution
-
Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset
- Function
- Important in regulating mucosal immune response
- Ligand/Receptor
- CCL20/MIP-3a
- Cell Type
- B cells, Dendritic cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Rossi D, et al. 1997. J. Immunol. 158:1033.
2. Lukacs N, et al. 2001. J. Exp. Med. 194:551.
3. Cook DN, et al. 2000. Immunity 12:495
- Gene ID
- 12458 View all products for this Gene ID
- UniProt
- View information about CD196 on UniProt.org
