Alexa Fluor® 647 anti-mouse CD196 (CCR6) Antib
- 产品名称：
- Alexa Fluor® 647 anti-mouse CD196 (CCR6) Antib
- 产品类别：
- 抗体
- 产品编号：
- 129807
- 产品应用：
- 129807
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
- Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
- Pack AD, et al. 2021. Cell Reports. 36(8):109586. PubMed
- Chen J et al. 2018. Cell reports. 25(12):3393-3404 . PubMed
- Shen X, et al. 2021. Front Immunol. 12:710750. PubMed
- Nguyen HD, et al. 2020. Cell Rep. 33:108316. PubMed
- RRID
- AB_1227498 (BioLegend Cat. No. 129807) AB_1227497 (BioLegend Cat. No. 129808)
- Structure
- G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6
- Distribution
-
Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset
- Function
- Important in regulating mucosal immune response
- Ligand/Receptor
- CCL20/MIP-3a
- Cell Type
- B cells, Dendritic cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Rossi D, et al. 1997. J. Immunol. 158:1033.
2. Lukacs N, et al. 2001. J. Exp. Med. 194:551.
3. Cook DN, et al. 2000. Immunity 12:495
- Gene ID
- 12458 View all products for this Gene ID
- UniProt
- View information about CD196 on UniProt.org
