Purified anti-ApoER2 (LRP8) Antibody
- 产品名称：
- Purified anti-ApoER2 (LRP8) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 862101
- 产品应用：
- 862101
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2801239 (BioLegend Cat. No. 862101) AB_2801240 (BioLegend Cat. No. 862102)
- Structure
- LRP8 is a 963 amino acid protein with an apparent molecular mass of ~105 kD.
- Distribution
-
Tissue Distribution: brain, endocrine tissue, testis, and placenta
Cellular Distribution: plasma membrane, extracellular, and cytoskeleton
- Function
- LRP8 functions as the receptor for reelin. Binding and endocytosis of reelin triggers downstream signaling pathways that affects neuronal migration and postnatal LTP.
- Interaction
- FE65, JIP1, JIP2, Thrombosphondin, F-Spondin
- Cell Type
- Neurons
- Biology Area
- Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
- Molecular Family
- Apolipoproteins
- Antigen References
-
- Santana J and Marzolo MP. 2017. Biochem J. 474(18):3137
- Kim J, et al. 2014. Mol Cells. 37(11):767
- Lara-Castillo N and Johnson ML. 2015. Rev Endocr Metab Disord. 16(2):141
- Gene ID
- 7804 View all products for this Gene ID 16975 View all products for this Gene ID
- UniProt
- View information about ApoER2 on UniProt.org
