APC anti-human CD273 (B7-DC, PD-L2) Antibody
- 产品名称：
- APC anti-human CD273 (B7-DC, PD-L2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 329608
- 产品应用：
- 329608
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3768 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human PD-L2 cDNA
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Brown JA, et al. 2003. J. Immunol. 170:1257
- Rodig N, et al. 2003. Eur. J. Immunol. 33:3117
- Product Citations
-
- Katsurahara K, et al. 2021. Cancer Sci. 112:1026. PubMed
- Semnani R, et al. 2011. Infect Immun. 79:3957. PubMed
- El Ahanidi H, et al. 2022. Front Oncol. 11:795242. PubMed
- Mulder K, et al. 2021. Immunity. 54(8):1883-1900.e5. PubMed
- Yeong J, et al. 2019. J Immunother Cancer. 7:34. PubMed
- Forsberg MH, et al. 2021. Stem Cell Res Ther. 12:459. PubMed
- Hunegnaw R, et al. 2019. Front Immunol. 1.484027778. PubMed
- RRID
- AB_1089013 (BioLegend Cat. No. 329608)
- Structure
- B7 Immunoglobulin superfamily, 25 kD
- Distribution
-
Dendritic cells, liver, few transformed cell lines, subset of macrophages
- Function
- Binds to PD-1 and alternative receptor; ligation on DC stimulates, inhibits T cell responses via PD-1 binding, stimulates T cells via alternative receptor binding and promotes tumor immunity
- Ligand/Receptor
- PD-1
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
1. Shin T, et al. 2003. J. Exp. Med. 198:31.
2. Liu X, et al. 2003. J. Exp. Med. 197:1721.
3. Carreno BM, et al. 2002. Annu. Rev. Immunol. 20:29.
- Gene ID
- 80380 View all products for this Gene ID
- UniProt
- View information about CD273 on UniProt.org
