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Alexa Fluor® 647 anti-Nanog Antibody
产品名称:
Alexa Fluor® 647 anti-Nanog Antibody
产品类别:
抗体
产品编号:
674010
产品应用:
674010
[价格]
规格 价格 库存
100µg ¥ 4584 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length human recombinant protein expressed in bacteria
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear? Transcription Factor Staining Protocol.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application Notes

NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.

This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).

Product Citations
  1. Ababneh NA, et al. 2020. Stem Cell Research. 49:102000. PubMed
  2. Ababneh NA, et al. 2020. Stem Cell Research. 72.77986111. PubMed
  3. Ibuki M, et al. 2019. Regen Ther. 0.551388889. PubMed
  4. Ababneh NA, et al. 2020. Stem Cell Research. 48:101967. PubMed
RRID
AB_2632605 (BioLegend Cat. No. 674010)

Antigen Details

Structure
305 amino acids with a predicted molecular weight of approximately 35 kD.
Distribution

Nuclear and cytoplasmic. Expressed by embryonic stem (ES) cells or cancer stem cells. Expression decreases with ES differentiation.

Function
Transcription regulator that plays key roles in the maintenance of pluripotency and self-renewal in embryonic stem cells.
Interaction
Interacts with SMAD1, SALL4, and ZNF281/ZFP281.
Cell Type
Embryonic Stem Cells
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Signal Transduction, Stem Cells, Transcription Factors
Antigen References

1. Hwang CC, et al. 2014. PLoS One 9:e105676.
2. Torres-Padilla ME, et al. 2014. Development 141:2173.
3. Iv Santaliz-Ruiz LE, et al. 2014. Int. J. Cancer 12:2741.
4. Wang ML, et al. 2013. Onco. Targets Ther. 6:1207.
5. Kim J, et al. 2008. Cell 132:1049.
6. Takahashi K, et al. 2007. Nat. Protoc. 2:3081.
7. Yu J, et al. 2007. Science 318:1917.

Gene ID
79923 View all products for this Gene ID
UniProt
View information about Nanog on UniProt.org

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