Purified anti-mouse TSLPR (TSLP-R) Antibody
- 产品名称：
- Purified anti-mouse TSLPR (TSLP-R) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 151802
- 产品应用：
- 151802
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- TSLP Receptor Protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Isaksen DE, et al. 2002. J. Immunol. 168:3288. (FC)
- Bell BD, et al. 2013. Nat. Immunol. 14:364. (FC)
- Iseki M, et al. 2012. International Immunology 24:183. (FC)
- Astrakhan A, et al. 2007. Nature Immunology 8:522. (FC)
- RRID
- AB_2616861 (BioLegend Cat. No. 151802)
- Structure
- Type I membrane receptor, forms functional heterodimeric complex with IL-7R to bind TSLP. Contains WSXWS motif required for proper protein folding and a box1 motif that is important for association with the JAKs.
- Distribution
- Expressed preferentially in myeloid cells including dendritic cells, B cells, activated monocytes, weakly expressed in T cells. Also expressed in heart, skeletal, muscle, and kidney cells.
- Function
- Binds to TSLP to stimulate cell proliferation.
- Ligand/Receptor
- TSLP.
- Cell Type
- Dendritic cells, B cells, Monocytes
- Biology Area
- Immunology
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Reche PA, et al. 2001. J. Immunol. 167:336.
2. Tonozuka Y, et al. 2001. Cytogenet. Cell Genet. 93:23.
3. Zhang W, et al. 2001. Biochem. Biophys. Res. Commun. 281:878.
4. Wang YH, et al. 2006. Immunity 24:827.
- Gene ID
- 57914 View all products for this Gene ID
- UniProt
- View information about TSLPR on UniProt.org
