Brilliant Violet 421™ anti-mouse TSLPR (TSLP-上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 3504	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

TSLP Receptor Protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).

Preparation

The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.?

Learn more about Brilliant Violet?.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.

Excitation Laser

Violet Laser (405 nm)

Application References (PubMed link indicates BioLegend citation)

Isaksen DE, et al. 2002. J. Immunol. 168:3288. (FC)
Bell BD, et al. 2013. Nat. Immunol. 14:364. (FC)
Iseki M, et al. 2012. International Immunology 24:183. (FC)
Astrakhan A, et al. 2007. Nature Immunology 8:522. (FC)

Product Citations

Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed

RRID

AB_2687305 (BioLegend Cat. No. 151807)

Antigen Details

Structure: Type I membrane receptor, forms functional heterodimeric complex with IL-7R to bind TSLP. Contains WSXWS motif required for proper protein folding and a box1 motif that is important for association with the JAKs.
Distribution: Expressed preferentially in myeloid cells including dendritic cells, B cells, activated monocytes, weakly expressed in T cells. Also expressed in heart, skeletal, muscle, and kidney cells.
Function: Binds to TSLP to stimulate cell proliferation.
Ligand/Receptor: TSLP
Cell Type: Dendritic cells, B cells, Monocytes
Biology Area: Immunology
Molecular Family: Cytokine/Chemokine Receptors
Antigen References: 1. Reche PA,?et al.?2001.?J. Immunol.?167:336.
2. Tonozuka Y,?et al.?2001.?Cytogenet. Cell Genet.?93:23.
3. Zhang W,?et al.?2001.?Biochem. Biophys. Res. Commun.?281:878.
4. Wang YH,?et al.?2006.?Immunity?24:827.
Gene ID: 57914 View all products for this Gene ID
UniProt: View information about TSLPR on UniProt.org

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