APC anti-mouse TSLPR (TSLP-R) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1788	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

TSLP Receptor Protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Red Laser (633 nm)

Application References (PubMed link indicates BioLegend citation)

Isaksen DE, et al. 2002. J. Immunol. 168:3288. (FC)
Bell BD, et al. 2013. Nat. Immunol. 14:364. (FC)
Iseki M, et al. 2012. International Immunology 24:183. (FC)
Astrakhan A, et al. 2007. Nature Immunology 8:522. (FC)

RRID

AB_2650788 (BioLegend Cat. No. 151805) AB_2650789 (BioLegend Cat. No. 151806)

Antigen Details

Structure: Type I membrane receptor, forms functional heterodimeric complex with IL-7R to bind TSLP. Contains WSXWS motif required for proper protein folding and a box1 motif that is important for association with the JAKs.
Distribution: Expressed preferentially in myeloid cells including dendritic cells, B cells, activated monocytes, weakly expressed in T cells. Also expressed in heart, skeletal, muscle, and kidney cells.
Function: Binds to TSLP to stimulate cell proliferation.
Ligand/Receptor: TSLP
Cell Type: Dendritic cells, B cells, Monocytes
Biology Area: Immunology
Molecular Family: Cytokine/Chemokine Receptors
Antigen References: 1. Reche PA,?et al.?2001.?J. Immunol.?167:336.
2. Tonozuka Y,?et al.?2001.?Cytogenet. Cell Genet.?93:23.
3. Zhang W,?et al.?2001.?Biochem. Biophys. Res. Commun.?281:878.
4. Wang YH,?et al.?2006.?Immunity?24:827.
Gene ID: 57914 View all products for this Gene ID
UniProt: View information about TSLPR on UniProt.org

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