热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
PE anti-mouse/human Helios Antibody
产品名称：
PE anti-mouse/human Helios Antibody
产品类别：
抗体
产品编号：
137206
产品应用：
137206
[价格]
规格 价格 库存
25tests ￥ 2568 1

产品详情

Product Details

Verified Reactivity
Mouse, Human
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Helios peptide (aa 51-107)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear? Transcription Factor Staining Protocol. It is recommended that the reagent be titrated for optimal performance for each application.
For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended over the Foxp3 Fix/Perm Buffer Set (Cat. No. 421403) and the True-Nuclear? 10X Perm Buffer (Cat. No. 424403).

View more applications data for a different format of this clone in our Scientific Poster Library.

Application References

(PubMed link indicates BioLegend citation)
  1. Thornton AM, et al. 2010. J. Immunol. 184:1. PubMed
  2. Verhagen J and Wraith D. 2010. J. Immunol. 185:7129.
  3. Stone B, et al. 2012. Clin Immunol. 145:153. PubMed
  4. Vaeth M, et al. 2012. PNAS. 109:16258. PubMed
  5. Angin M, et al. 2014. PLoS One. 9:86920. PubMed
  6. Bedke T, et al. 2014. Immunol Cell Biol. PubMed
  7. Liu Y, et al. 2014. Am J Physiol Gastrointest Liver Physiol. 307:177. PubMed
  8. Verhagen J and Wraith DC. 2014. J. Immunol. Methods. S0022. (FC) PubMed
Product Citations
  1. Hatam L, et al. 2012. Clin Cancer Res. 2.086805556. PubMed
  2. Fuhrman C, et al. 2015. J Immunol. 195: 145 - 155. PubMed
  3. McClymont S, et al. 2011. J Immunol. 186:3918. PubMed
  4. Zeng Z, et al. 2016. J Exp Med. 213: 1079 - 1093. PubMed
  5. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  6. Spallanzani R, et al. 2015. J Immunol. 195: 2141-2148. PubMed
  7. MaruYama T 2015. Biochem Biophys Res Commun. 464: 586-589. PubMed
  8. Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
  9. Baine I, et al. 2013. J Immunol. 190:1008. PubMed
  10. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  11. Dean JW, et al. 2020. J Autoimmun. 108:102417. PubMed
  12. Trotta E, et al. 2018. Nat Med. 24:1005. PubMed
  13. Sawanobori Y, et al. 2021. Histochem Cell Biol. 156:133. PubMed
  14. Zeng Z, et al. 2013. J Immunol. 191:4184. PubMed
  15. Goodwin M, et al. 2020. Sci Adv. 6:eaaz0571. PubMed
  16. Dehzad N, et al. 2011. J Immunol. 186:2238. PubMed
  17. Wraith J 2010. J Immunol. 185:7129. PubMed
  18. Alhosaini K, et al. 2021. Brain Sci. :11. PubMed
  19. Van Gool F, et al. 2019. Immunity. 50:362. PubMed
  20. Paiva R, et al. 2013. Proc Natl Acad Sci U S A. 110:6494. PubMed
  21. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  22. Yuan X, et al. 2017. Elife. 6:e29540. PubMed
  23. Ostadkarampour M, et al. 2016. PLoS One. 11:e0164751. PubMed
  24. Santoni de Sio FR, et al. 2018. J Allergy Clin Immunol. 142:1909. PubMed
  25. Redpath S, et al. 2015. Infect Immun . 83: 3881 - 3889. PubMed
  26. MaruYama T, et al. 2015. J Leukoc Biol. 98: 385-393. PubMed
  27. Kim YC, et al. 2018. J Immunol. 201:1671. PubMed
  28. Baron CS, et al. 2018. Nat Commun. 9:2517. PubMed
  29. Adel–Patient K, et al. 2018. Clin Transl Allergy. 8:38. PubMed
  30. Zhao J, et al. 2011. J Exp Med. 208:1571. PubMed
  31. Grinberg–Bleyer Y, et al. 2017. Cell. 170:1096. PubMed
RRID
AB_10552903 (BioLegend Cat. No. 137206) AB_10660749 (BioLegend Cat. No. 137216)

Antigen Details

Structure
A zinc finger nuclear transcription factor of the Ikaros family, containing 2 zinc-finger domains in C-terminal region.
Distribution

Regulatory T cells (Tregs), conventional T cells, thymocytes.

Function
Plays an important role in T cell development and homeostasis, involved in tumor immunity.
Cell Type
T cells, Thymocytes, Tregs
Biology Area
Cell Biology, Immunology, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Kelly CM, et al.? 1998. Curr. Biol. 8:508.
2. Dovat S, et al. 2005. J. Immunol. 175:3508.
3. Cortes M, et al. 1999. Curr. Opin. Immunol. 11:167.
4. Cai Q, et al. 2009. J. Immunol. 183:2303.
5. Zhang Z, et al. 2007. Blood 109:2190.
6. Hahm K, et al. 1998. Genes Dev. 12:782.

Gene ID
22779 View all products for this Gene ID 22807 View all products for this Gene ID
UniProt
View information about Helios on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线