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Purified anti-human CXCL16 Antibody
产品名称:
Purified anti-human CXCL16 Antibody
产品类别:
抗体
产品编号:
360802
产品应用:
360802
[价格]
规格 价格 库存
100µg ¥ 2748 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified human SR-PSOX-Fc fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats of this clone) include: in vitro blocking of chemotactic activity of CXCR6 expressing cells1. Clone 22-19-12 recognizes the chemokine domain of CXCL16 and has been shown to inhibit chemotactic activity to CXCR6-expressing cells by soluble CXCL16.1

Application References

(PubMed link indicates BioLegend citation)
  1. Shimaoka T, et al. 2003. J. Immunol. 171:1647. (FC, Block)
RRID
AB_2562794 (BioLegend Cat. No. 360802)

Antigen Details

Structure
~27 kD, exists as a membrane bound and soluble forms
Distribution
Produced by dendritic cells and T cells
Function
Binds to oxidized LDL and may play an important role in atherosclerosis
Interaction
Interacts with CXCR6/Bonzo
Ligand/Receptor
CXCR6
Cell Type
Dendritic cells, T cells
Biology Area
Immunology, Innate Immunity
Molecular Family
Cytokines/Chemokines
Antigen References

1. Matloubian M, et al. 2000. Nat. Immunol. 1:298.
2. Wilbanks A, et al. 2001. J. Immunol. 166:5145.
3. Shimaoka T, et al. 2003. J. Immuniol. 171:1647.
4. Chandrasekar B, et al. 2004. J. Biol. Chem. 179:3188.
5. Shimaoka T, et al. 2004. J. Leukoc. Biol. 75:267.

Gene ID
58191 View all products for this Gene ID
UniProt
View information about CXCL16 on UniProt.org

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