Purified anti-human CXCL16 Antibody
- 产品名称:
- Purified anti-human CXCL16 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 360802
- 产品应用:
- 360802
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified human SR-PSOX-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: in vitro blocking of chemotactic activity of CXCR6 expressing cells1. Clone 22-19-12 recognizes the chemokine domain of CXCL16 and has been shown to inhibit chemotactic activity to CXCR6-expressing cells by soluble CXCL16.1
- Application References
(PubMed link indicates BioLegend citation) -
- Shimaoka T, et al. 2003. J. Immunol. 171:1647. (FC, Block)
- RRID
- AB_2562794 (BioLegend Cat. No. 360802)
- Structure
- ~27 kD, exists as a membrane bound and soluble forms
- Distribution
- Produced by dendritic cells and T cells
- Function
- Binds to oxidized LDL and may play an important role in atherosclerosis
- Interaction
- Interacts with CXCR6/Bonzo
- Ligand/Receptor
- CXCR6
- Cell Type
- Dendritic cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Matloubian M, et al. 2000. Nat. Immunol. 1:298.
2. Wilbanks A, et al. 2001. J. Immunol. 166:5145.
3. Shimaoka T, et al. 2003. J. Immuniol. 171:1647.
4. Chandrasekar B, et al. 2004. J. Biol. Chem. 179:3188.
5. Shimaoka T, et al. 2004. J. Leukoc. Biol. 75:267.
- Gene ID
- 58191 View all products for this Gene ID
- UniProt
- View information about CXCL16 on UniProt.org