PE anti-human CXCL16 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1836	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Purified human SR-PSOX-Fc fusion protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

Additional reported applications (for the relevant formats of this clone) include: in vitro blocking of chemotactic activity of CXCR6 expressing cells¹. Clone 22-19-12 recognizes the chemokine domain of CXCL16 and has been shown to inhibit chemotactic activity to CXCR6-expressing cells by soluble CXCL16.¹

Application References (PubMed link indicates BioLegend citation)

Shimaoka T, et al. 2003. J. Immunol. 171:1647. (FC, Block)

Product Citations

Gouwy M, et al. 2016. PLoS One. 11:e0166006. PubMed

RRID

AB_2563010 (BioLegend Cat. No. 360803) AB_2563011 (BioLegend Cat. No. 360804)

Antigen Details

Structure: ~27 kD, exists as a membrane bound and soluble forms
Distribution: Produced by dendritic cells and T cells
Function: Binds to oxidized LDL and may play an important role in atherosclerosis
Interaction: Interacts with CXCR6/Bonzo
Ligand/Receptor: CXCR6
Cell Type: Dendritic cells, T cells
Biology Area: Immunology, Innate Immunity
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Matloubian M, et al. 2000. Nat. Immunol. 1:298.
2. Wilbanks A, et al. 2001. J. Immunol. 166:5145.
3. Shimaoka T, et al. 2003. J. Immuniol. 171:1647.
4. Chandrasekar B, et al. 2004. J. Biol. Chem. 179:3188.
5. Shimaoka T, et al. 2004. J. Leukoc. Biol. 75:267.
Gene ID: 58191 View all products for this Gene ID
UniProt: View information about CXCL16 on UniProt.org

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