Purified anti-human CD244 (2B4) Antibody
- 产品名称：
- Purified anti-human CD244 (2B4) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 393502
- 产品应用：
- 393502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human NK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP, Cyt - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: redirected killing assays (rADCC) in NK cells1.
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H,?et al. 2000.?Eur J Immunol. 30:3309.?(Cytotoxicity, IP)
- Tassi I, Colonna M. 2005.?J. Immunol.?7996-8002. (IP)
- RRID
- AB_2728427 (BioLegend Cat. No. 393502)
- Structure
- 38 kD type I transmembrane protein, CD2 family member, Ig superfamily
- Distribution
-
NK, T subset, monocytes, basophils, and eosinophils
- Function
- Activation and inhibition of NK cell function
- Ligand/Receptor
- CD48
- Cell Type
- Basophils, Eosinophils, Monocytes, NK cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Lee KM, et al. 2003. J. Immunol. 170:4881.
- Chlewicki LK, et al. 2008. J. Immunol. 180:8159.
- Messmer B, et al. 2006. J. Immunol. 176:4646.
- Boles KS, et al. 2001. Immunol. Rev. 181:234.
- Gene ID
- 51744 View all products for this Gene ID
- UniProt
- View information about CD244 on UniProt.org
