PE/Dazzle™ 594 anti-human CD244 (2B4) Antibo
- 产品名称：
- PE/Dazzle™ 594 anti-human CD244 (2B4) Antibo
- 产品类别：
- 抗体
- 产品编号：
- 393506
- 产品应用：
- 393506
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3696 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human NK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle? 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PE/Dazzle? 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: redirected killing assays (rADCC) in NK cells1.
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H,?et al. 2000.?Eur J Immunol. 30:3309.?(Cytotoxicity, IP)
- Tassi I, Colonna M. 2005.?J. Immunol.?7996-8002. (IP)
- Product Citations
-
- Sekine T, et al. 2020. Cell. 183:158. PubMed
- RRID
- AB_2734463 (BioLegend Cat. No. 393505) AB_2734464 (BioLegend Cat. No. 393506)
- Structure
- 38 kD type I transmembrane protein, CD2 family member, Ig superfamily
- Distribution
-
NK, T subset, monocytes, basophils, and eosinophils
- Function
- Activation and inhibition of NK cell function
- Ligand/Receptor
- CD48
- Cell Type
- Basophils, Eosinophils, Monocytes, NK cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Lee KM, et al. 2003. J. Immunol. 170:4881.
- Chlewicki LK, et al. 2008. J. Immunol. 180:8159.
- Messmer B, et al. 2006. J. Immunol. 176:4646.
- Boles KS, et al. 2001. Immunol. Rev. 181:234.
- Gene ID
- 51744 View all products for this Gene ID
- UniProt
- View information about CD244 on UniProt.org
