Purified anti-human CD221 (IGF-1R) Antibody
- 产品名称:
- Purified anti-human CD221 (IGF-1R) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 351802
- 产品应用:
- 351802
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- IGF-1 receptor purified from human placentas
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC, IP, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This clone has been published as 1H7. Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, immunohistochemical staining of frozen tissue sections2, and blocking functions2-5.
This product is offered for sale and sold pursuant to a license to seller by City of Hope and may be used only as a research reagent.? Use for any other purpose is expressly not authorized.
- Application References
(PubMed link indicates BioLegend citation) -
- Li SL, et al. 1993. Biochem. Bioph. Res. Co. 196:92. (WB IP)
- Li SL, et al. 2000. Cancer Immunol. Immun. 49:243. (IHC Block)
- Ye JJ, et al. 2003. Horm. Metab. Res. 35:836. (Block)
- Kusada Y, et al. 2008. J. Biochem. 143:9. (Block)
- Ohtani M, et al. 2009. Biosci. Trends. 3:131. (Block)
- RRID
- AB_10896950 (BioLegend Cat. No. 351802)
- Structure
- IGF-1R contains 2 α subunits and 2 β subunits, 135 kD
- Distribution
-
Haematopoietic cells and non-haematopoietic cells
- Function
- Cell growth and immune cells recruitment
- Ligand/Receptor
- IGF-1, IGF-2
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Baudler S, et al. 2005. J. Immunol. 174:5516.
2. Sharp LL, et al. 2005. Nat. Immunol. 6:73.
- Gene ID
- 3480 View all products for this Gene ID
- UniProt
- View information about CD221 on UniProt.org