Purified anti-C/EBP β (3 isoforms C/EBP &beta
- 产品名称:
- Purified anti-C/EBP β (3 isoforms C/EBP &beta
- 产品类别:
- 抗体
- 产品编号:
- 606202
- 产品应用:
- 606202
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant LIP
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ChIP, IP, ICC?- Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 ?g antibody per 5 mL?antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Recognizes three mouse isoforms: C/EBP ?, LAP, LIP. Does not?cross-react with human.
- Application References
(PubMed link indicates BioLegend citation) -
- Su, et al. 2003. J. Biol. Chem. 278:51150. (ChIP)
- Blidner AG, et al. 2015. J Immunol. 194:3452. PubMed
- Product Citations
-
- Huang JQ, et al. 2021. Front Mol Biosci. 8:725275. PubMed
- Ebert SM, et al. 2020. J Biol Chem. 295:2787. PubMed
- Blidner A, et al. 2015. J Immunol. 194:3452. PubMed
- Sharma N, et al. 2021. Front Mol Biosci. 7:603168. PubMed
- RRID
- AB_315675 (BioLegend Cat. No. 606202)
- Structure
- C/EBP transcription factor family, basic leucine zipper, dimer. Isoforms C/EBPβ, LAP, LIP, approximately 35 kD, 32 kD, 20 kD, respectively
- Distribution
-
Nuclear
- Function
- Transcription factor in immune, inflammatory, acute-phase, cytokine, collagen type I genes
- Interaction
- CEBP-α, CEBP-β, CEBP-δ, CEBP-γ, CEBP-ε, CEBP-ζ
- Modification
- Phosphorylation, Ubiquitination
- Biology Area
- Cell Biology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Chang C, et al. 1990. Mol. Cell Biol. 10:6642.
2. Eaton E, et al. 2001. J. Cell Physiol. 189:91.
3. Piwien-Pilipuk G, et al. 2002. J. Biol. Chem. 277:44557.
4. Hattori T, et al. 2003. Oncogene. 22:1273.
- Regulation
- Growth hormone
- Gene ID
- 12608 View all products for this Gene ID 25301 View all products for this Gene ID
- UniProt
- View information about C/EBP beta on UniProt.org