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Purified anti-BID Antibody
产品名称:
Purified anti-BID Antibody
产品类别:
抗体
产品编号:
650502
产品应用:
650502
[价格]
规格 价格 库存
100µg ¥ 3180 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Bacteria expressed His tagged full length recombinant protein
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% NaN3.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, store undiluted between 2°C and 8°C.
Application

WB - Quality tested
ELISA - Reported by the developer, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 1.0 ?g antibody per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody recognizes full-length BID (22 kD) in Western blots, but not its cleaved form (tBID, 15 kD).

RRID
AB_10897951 (BioLegend Cat. No. 650502)

Antigen Details

Structure
195 aa encodes a 22 kD protein. It contains only BH3 domain, not the BH1, BH2, and BH4 domains found in other Bcl-2 family members.
Distribution

Cytoplasmic, inside mitochondria once activated.

Function
Activated by Caspase 8 in response to Fas/TNF-R1 death receptor signals.
Ligand/Receptor
Caspase-8, BAK
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology
Antigen References

1. Wang K, et al. 1996. Genes Dev. 10:2859.
2. Luo X, et al. 1998. Cell 94:481.
3. Yin XM, et al. 1999. Nature 400:886 .
4. Strasser A, et al. 2009. Immunity 30:180.

Gene ID
637 View all products for this Gene ID
UniProt
View information about BID on UniProt.org

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