Purified anti-BID Antibody
- 产品名称:
- Purified anti-BID Antibody
- 产品类别:
- 抗体
- 产品编号:
- 650502
- 产品应用:
- 650502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Bacteria expressed His tagged full length recombinant protein
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% NaN3.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ELISA - Reported by the developer, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 1.0 ?g antibody per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody recognizes full-length BID (22 kD) in Western blots, but not its cleaved form (tBID, 15 kD).
- RRID
- AB_10897951 (BioLegend Cat. No. 650502)
- Structure
- 195 aa encodes a 22 kD protein. It contains only BH3 domain, not the BH1, BH2, and BH4 domains found in other Bcl-2 family members.
- Distribution
-
Cytoplasmic, inside mitochondria once activated.
- Function
- Activated by Caspase 8 in response to Fas/TNF-R1 death receptor signals.
- Ligand/Receptor
- Caspase-8, BAK
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology
- Antigen References
-
1. Wang K, et al. 1996. Genes Dev. 10:2859.
2. Luo X, et al. 1998. Cell 94:481.
3. Yin XM, et al. 1999. Nature 400:886 .
4. Strasser A, et al. 2009. Immunity 30:180.
- Gene ID
- 637 View all products for this Gene ID
- UniProt
- View information about BID on UniProt.org