Purified anti-mouse P2X7R Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3732	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Murine colon mast cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IP, IHC, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications for the relevant formats include: immunoprecipitation¹, Western blotting¹, immunohistochemistry¹,?in vivo?inhibition of intestinal inflammation and mast cell activation¹.

Application References (PubMed link indicates BioLegend citation)

Kurashima Y, et al. 2012. Nat. Commun. 3:1034. (FC, IP, WB, IHC, FA)

Product Citations

Yan J, et al. 2020. Cancer Immunol Res. 8:356. PubMed
Guan F, et al. 2021. Infect Immun. 89: . PubMed
Islam J, et al. 2022. Front Immunol. 13:766919. PubMed

RRID

AB_2564122 (BioLegend Cat. No. 148702)

Antigen Details

Structure: Ligand-gated ion channel, trimer - two transmembrane regions and one cytosolic region.
Distribution: Immune cells, including mast cells, microglia, macrophages, T cells, and B cells.
Function: Ion channel activated by extracellular ATP.
Ligand/Receptor: ATP, NAD.
Cell Type: B cells, Macrophages, Mast cells, T cells, Tregs
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Antigen References: 1. Surprenant A, et al. 1996. Science.?272:735.
2. Chused TM, et al. 1996. J. Immunol. 157:1371.
3. Gargett CE, et al. 1997. Br. J. Pharmacol. 122:911.
4. Kawamura H, et al. 2006. J. Immunol. 176:2152.
5. Pelegrin P. 2011. Br. J. Pharmacol. 163:908.
6. Bartlett R, et al. 2014. Pharmacol. Rev. 66:638.
7. Alves LA, et al. 2014. Biochim. Biophys. Acta. 1838:2578.
Gene ID: 18439 View all products for this Gene ID
UniProt: View information about P2X7R on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们