Purified anti-IMPDH1 Antibody
- 产品名称:
- Purified anti-IMPDH1 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 935201
- 产品应用:
- 935201
- Verified Reactivity
- Human, Mouse, Hamster
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length IMPDH purified from a Chinese hamster V79 cell variant
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IP, ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g/mL.?For immunoprecipitation, the suggested use of this reagent is 2.5 ?g/test.?For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone recognizes human, mouse and hamster IMPDH1 and is predicted to recognize the rodent orthologs. Clone is likely to cross react with IMPDH2.
For ICC testing, HeLa cells were fixed in 4% PFA and permeabilized with either Triton X-100 or methanol; both methods produced strong staining at 1 ?g/mL.
- RRID
- AB_2832890 (BioLegend Cat. No. 935201) AB_2832891 (BioLegend Cat. No. 935202)
- Structure
- IMPDH1 is an 514 aminoacid protein with a predicted molecular weight of 56 kD.
- Distribution
-
Localized to the cytosol filamentous rods and rings / Ubiquitously expressed
- Function
- Regulation of cell growth, and biosynthesis of de novo GTP
- Biology Area
- Cell Cycle/DNA Replication, Cell Proliferation and Viability, DNA Repair/Replication
- Antigen References
-
- Calise SJ, et al. 2015. Front Immunol. 6:41.
- Liao LX, et al. 2017. Proc Natl Acad Sci U S A. 29.
- Duan S, et al. 2018. J Exp Clin Cancer Res. 37:304.
- Zhao Y, et al. 2018. Biomarkers. 1:9.
- Carcamo WC, et al. 2011. PLoS One. 6.
- Xu Y, et al. 2017. Sci Rep. 7:745.
- Glesne DA, et al. 1991. Mol Cell Biol. 11:5417-25.
- Hager PW, et al. 1995. Biochem Pharmacol. 49:1323-9.
- Gene ID
- 3614 View all products for this Gene ID
- UniProt
- View information about IMPDH1 on UniProt.org