首页 > 抗体蛋白 > 抗体
Purified anti-IMPDH1 Antibody
产品名称:
Purified anti-IMPDH1 Antibody
产品类别:
抗体
产品编号:
935201
产品应用:
935201
[价格]
规格 价格 库存
25µg ¥ 1212 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Hamster
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length IMPDH purified from a Chinese hamster V79 cell variant
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IP, ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g/mL.?For immunoprecipitation, the suggested use of this reagent is 2.5 ?g/test.?For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone recognizes human, mouse and hamster IMPDH1 and is predicted to recognize the rodent orthologs. Clone is likely to cross react with IMPDH2.

For ICC testing, HeLa cells were fixed in 4% PFA and permeabilized with either Triton X-100 or methanol; both methods produced strong staining at 1 ?g/mL.

RRID
AB_2832890 (BioLegend Cat. No. 935201) AB_2832891 (BioLegend Cat. No. 935202)

Antigen Details

Structure
IMPDH1 is an 514 aminoacid protein with a predicted molecular weight of 56 kD.
Distribution

Localized to the cytosol filamentous rods and rings / Ubiquitously expressed

Function
Regulation of cell growth, and biosynthesis of de novo GTP
Biology Area
Cell Cycle/DNA Replication, Cell Proliferation and Viability, DNA Repair/Replication
Antigen References
  1. Calise SJ, et al. 2015. Front Immunol. 6:41.
  2. Liao LX, et al. 2017. Proc Natl Acad Sci U S A. 29.
  3. Duan S, et al. 2018. J Exp Clin Cancer Res. 37:304.
  4. Zhao Y, et al. 2018. Biomarkers. 1:9.
  5. Carcamo WC, et al. 2011. PLoS One. 6.
  6. Xu Y, et al. 2017. Sci Rep. 7:745.
  7. Glesne DA, et al. 1991. Mol Cell Biol. 11:5417-25.
  8. Hager PW, et al. 1995. Biochem Pharmacol. 49:1323-9.
Gene ID
3614 View all products for this Gene ID
UniProt
View information about IMPDH1 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线