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Purified anti-TDP43 Phospho (Ser409/410) Antibody
产品名称:
Purified anti-TDP43 Phospho (Ser409/410) Antibody
产品类别:
抗体
产品编号:
829901
产品应用:
829901
[价格]
规格 价格 库存
100µL ¥ 4356 1

产品详情

Product Details

Verified Reactivity
Human, Rat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
This antibody was raised against a phosphopeptide corresponding to: i) the C-terminal domain of human TDP43; and ii) inclusive of phosphorylated serine residues 409 and 410.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB - Quality tested
IHC, ICC, ELISA- Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting.

The optimal working dilution should be determined for each specific assay condition.
? WB: 1:1,000
?

Application Notes

This antibody is effective in immunoblotting (WB)

Positive Control: Rat Brain nuclear lysate
Expected MW: ~43 kD

Application References

(PubMed link indicates BioLegend citation)
  1. Neumann M, et al. 2009. Acta Neuropathol. 117:137-49.
  2. Sarroukh R, et al. 2011. Cell Mol Life Sci. 68:1429. (WB, IHC, ELISA, IF)
  3. Ramakrishnan M, et al. 2009. Biochemistry 48:10405. (WB)
  4. Watts JC, et al. 2014. Proc. Natl. Acad. Sci. USA. 111:10323. (WB, IHC)
  5. Diomede L, et al. 2014. Neurobiol Dis. 62:521. (IHC)
Product Citations
  1. Gasset-Rosa F, et al. 2019. Neuron. 102:339. PubMed
  2. Gleixner AM, et al. 2022. Nat Commun. 13:3380. PubMed
  3. Liu EA, et al. 2021. Neuropathol Appl Neurobiol. 47:1019. PubMed
  4. Wiesner D, et al. 2017. Exp Neurol. 10.1016/j.expneurol.2017.09.011. PubMed
  5. Wani A, et al. 2021. Cell Reports. 36(3):109399. PubMed
RRID
AB_2564934 (BioLegend Cat. No. 829901)

Antigen Details

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
Phospho-Proteins, TDP43
Gene ID
23435 View all products for this Gene ID 298648 View all products for this Gene ID
UniProt
View information about TDP43 Phospho Ser409/Ser410 on UniProt.org

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