PE anti-mouse CD19 Antibody
- 产品名称：
- PE anti-mouse CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 152407
- 产品应用：
- 152407
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Transfected k562 cells expressing the extracellular domain of murine CD19.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.
- Application References
(PubMed link indicates BioLegend citation) -
- Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP)
- Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)
- Product Citations
-
- Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
- Kurosawa M, et al. 2021. Int J Mol Sci. 22:. PubMed
- Westerterp M et al. 2017. Cell metabolism. 25(6):1294-1304 . PubMed
- Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
- Amor C, et al. 2020. Nature. 583:127. PubMed
- Zhou Y, et al. 2022. Nat Commun. 13:2906. PubMed
- Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
- Cha SE, et al. 2021. Oncoimmunology. 10:1899469. PubMed
- Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
- Kobayashi M, et al. 2020. Bio Protoc. 10:e3601. PubMed
- Zhong W, et al. 2022. Nat Commun. 13:4390. PubMed
- Tartey S, et al. 2021. Cancer Research. 81(9):2358-2372. PubMed
- Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
- La Rose AM, et al. 2021. Mol Metab. 53:101265. PubMed
- Zeng Z, et al. 2022. Oncogene. :. PubMed
- Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
- Huang D, et al. 2020. Nat Commun. 4.520833333. PubMed
- Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
- RRID
- AB_2629816 (BioLegend Cat. No. 152407) AB_2629817 (BioLegend Cat. No. 152408)
- Structure
- Ig superfamily, associates with CD21 and CD81, 95 kD.
- Distribution
-
Pro-B cells to mature B cells (during development), follicular dendritic cells.
- Function
- Modulates B cell activation and differentiation.
- Ligand/Receptor
- CD21, CD81, Leu-13.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF, et al. 1994. Immunol. Today 15:437.
- Gene ID
- 12478 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
