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FITC anti-mouse CD19 Antibody
产品名称:
FITC anti-mouse CD19 Antibody
产品类别:
抗体
产品编号:
152403
产品应用:
152403
[价格]
规格 价格 库存
25µg ¥ 852 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Transfected k562 cells expressing the extracellular domain of murine CD19.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.

Application References

(PubMed link indicates BioLegend citation)
  1. Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP)
  2. Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)
Product Citations
  1. Chei S, et al. 2020. Front Nutr. 7:583186. PubMed
  2. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  3. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  4. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  5. Hu HJ, et al. 2020. Cell Death Dis. 1.168055556. PubMed
  6. Zhao J, et al. 2019. Nat Commun. 10:899. PubMed
  7. Suzuki Y, et al. 2022. Mol Ther Nucleic Acids. 30:226. PubMed
  8. Liang Y, et al. 2020. J Immunol. 204:2984. PubMed
  9. Molina-Sanchez P, et al. 2020. Gastroenterology. 2203:159. PubMed
  10. Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed
  11. Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed
  12. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  13. Jassinskaja M, et al. 2021. Cell Reports. 34(12):108894. PubMed
  14. Cha SE, et al. 2021. Oncoimmunology. 10:1899469. PubMed
  15. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  16. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  17. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  18. Tavazoie MF, et al. 2018. Cell. 172:825. PubMed
  19. Zhou G, et al. 2019. FASEB J. 33:11396. PubMed
  20. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  21. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  22. Niderla-Bielinska J, et al. 2021. Int J Mol Sci. :22. PubMed
  23. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  24. Gomzikova MO, et al. 2020. Pharmaceutics. 12:00. PubMed
  25. Silva HM, et al. 2019. J Exp Med. 216:786. PubMed
  26. Tanegashima K et al. 2017. EBioMedicine. 24:247-256 . PubMed
  27. Whiteley AM et al. 2017. eLife. 6 pii: e26435. PubMed
  28. Jiang W, et al. 2021. Cell Rep. 37:110112. PubMed
RRID
AB_2629812 (BioLegend Cat. No. 152403) AB_2629813 (BioLegend Cat. No. 152404)

Antigen Details

Structure
Ig superfamily, associates with CD21 and CD81, 95 kD.
Distribution

Pro-B cells to mature B cells (during development), follicular dendritic cells.

Function
Modulates B cell activation and differentiation.
Ligand/Receptor
CD21, CD81, Leu-13.
Cell Type
B cells, Dendritic cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF, et al. 1994. Immunol. Today 15:437.

Gene ID
12478 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

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