APC anti-mouse CD19 Antibody
- 产品名称：
- APC anti-mouse CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 152409
- 产品应用：
- 152409
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Transfected k562 cells expressing the extracellular domain of murine CD19.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.
- Application References
(PubMed link indicates BioLegend citation) -
- Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP)
- Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)
- Product Citations
-
- Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed
- Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
- Prystaz K, et al. 2018. Am J Pathol. 188:474. PubMed
- Thompson PJ et al. 2019. Cell metabolism. 29(5):1045-1060 . PubMed
- Hering L, et al. 2021. Int J Mol Sci. 22:. PubMed
- Dignum T, et al. 2021. Cell Rep. 36:109675. PubMed
- Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
- Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
- Zhang F, et al. 2019. Immunity. 50:738. PubMed
- Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
- Liang Z, et al. 2020. Pain. 161:2089. PubMed
- Frazier T, et al. 2018. Adipocyte. 0.41875. PubMed
- Haase C, et al. 2022. Nat Methods. 19:1622. PubMed
- Bonglack EN, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
- Leal AS, et al. 2019. Sci Rep. 5.286111111. PubMed
- Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed
- Wang X, et al. 2018. Cell Death Dis. 9:578. PubMed
- Li H, et al. 2019. Front Immunol. 2.205555556. PubMed
- Oka Y, et al. 2020. Sci Adv. 6:. PubMed
- Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed
- Nordin F, et al. 2020. BMC Pregnancy and Childbirth. 20(1):399. PubMed
- Li E, et al. 2021. Front Immunol. 12:667177. PubMed
- Tuong ZK, et al. 2021. Cell Rep. 37:110132. PubMed
- Thürmer M, et al. 2022. Nat Commun. 13:2982. PubMed
- Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
- Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
- Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
- Lee A, et al. 2022. Nat Commun. 13:549. PubMed
- Chonwerawong M, et al. 2020. Gastroenterology. 159:169. PubMed
- Spath S, et al. 2022. iScience. 25:104998. PubMed
- RRID
- AB_2629838 (BioLegend Cat. No. 152409) AB_2629839 (BioLegend Cat. No. 152410)
- Structure
- Ig superfamily, associates with CD21 and CD81, 95 kD.
- Distribution
-
Pro-B cells to mature B cells (during development), follicular dendritic cells.
- Function
- Modulates B cell activation and differentiation.
- Ligand/Receptor
- CD21, CD81, Leu-13.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF, et al. 1994. Immunol. Today 15:437.
- Gene ID
- 12478 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
