PerCP/Cyanine5.5 anti-human CD365 (Tim-1) Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-human CD365 (Tim-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353911
- 产品应用：
- 353911
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2196 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TIM-1-IgV Fc
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.?
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported application (for the relevant formats) include: blocking function1.
- Application References
(PubMed link indicates BioLegend citation) -
- Freeman GJ, et al. 2007. Immunity. 27:927. (Block)
- RRID
- AB_2860929 (BioLegend Cat. No. 353911) AB_2860930 (BioLegend Cat. No. 353912)
- Structure
- Type 1 transmembrane glycoprotein.
- Distribution
-
Activated CD4+ lymphocytes, especially on Th2 cells.
- Function
- TIM-1 ligation induces T cell proliferation, promotes cytokine production, and aids in the regulation of Th2 immunity.
- Ligand/Receptor
- TIM-4
- Cell Type
- Dendritic cells, T cells, Th2
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Freeman GJ, et al. 2007. Immunity. 27:927.
2. Meyers JH, et al. 2005. Nat. Immunol. 6:455.
3. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454.
4. Mariat C, et al. 2005. Philos. Trans. R. Soc. Lond. B. 360:1681.
5. Yamanishi Y, et al. 2010. J. Exp. Med. 207:1501.
- Gene ID
- 26762 View all products for this Gene ID
- UniProt
- View information about CD365 on UniProt.org
