PE anti-human CD365 (Tim-1) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1836	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human TIM-1-IgV Fc

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

Additional reported application (for the relevant formats) include: blocking function¹.

Application References (PubMed link indicates BioLegend citation)

Freeman GJ, et al. 2007. Immunity. 27:927. (Block)

Product Citations

Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
Aravena O, et al. 2017. Arthritis Res Ther. 19:8. PubMed
Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
Smith CM, et al. 2021. Biochem J. 478:3331. PubMed

RRID

AB_11125165 (BioLegend Cat. No. 353903) AB_11125175 (BioLegend Cat. No. 353904)

Antigen Details

Structure: Type 1 transmembrane glycoprotein.
Distribution: Activated CD4⁺ lymphocytes, especially on Th2 cells.
Function: TIM-1 ligation induces T cell proliferation, promotes cytokine production, and aids in the regulation of Th2 immunity.
Ligand/Receptor: TIM-4
Cell Type: Dendritic cells, T cells, Th2
Biology Area: Immunology, Inhibitory Molecules
Molecular Family: CD Molecules
Antigen References: 1. Freeman GJ, et al. 2007. Immunity. 27:927.
2. Meyers JH, et al. 2005. Nat. Immunol. 6:455.
3. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454.
4. Mariat C, et al. 2005. Philos. Trans. R. Soc. Lond. B. 360:1681.
5. Yamanishi Y, et al. 2010. J. Exp. Med. 207:1501.
Gene ID: 26762 View all products for this Gene ID
UniProt: View information about CD365 on UniProt.org

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