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首页 > 抗体蛋白 > 抗体
Purified anti-mouse/rat CD42d Antibody
产品名称：
Purified anti-mouse/rat CD42d Antibody
产品类别：
抗体
产品编号：
148501
产品应用：
148501
[价格]
规格 价格 库存
50µg ￥ 1488 1

产品详情

Product Details

Verified Reactivity
Mouse, Rat
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse platelets
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for relevant formats) include: immunoprecipitation1,3.

Application References

(PubMed link indicates BioLegend citation)
  1. Takada K, et al. 1995. Hybridoma. 14:361. (IP)
  2. Saito M, et al. 1996. Stem Cells. 14:124. (FC)
  3. Sato N, et al. 2000. Hybridoma. 19:455. (IP)
RRID
AB_2564114 (BioLegend Cat. No. 148501)

Antigen Details

Structure
83 kD heterodimer composed of 2 polypeptide chains, an α chain (GP1BA) and a β chain (GP1BB).
Distribution

Resting platelets and megakaryocytes.

Function
CD42d is a component of the GPIb-V-IX complex, functions as a vWF receptor, and mediates vWF-dependent platelet adhesion to blood vessels.
Ligand/Receptor
CD42d.
Cell Type
Megakaryocytes, Platelets
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Sivaraman B, et al. 2011. Biomaterials. 32:5365.
2. Berger G, et al. 1996. Blood. 87:1385.
3. Ravanat C, et al. 1997. Blood. 89:3253.
4. Andrews RK, et al. 1998. Biochemistry. 37:638.
5. Inoue O, et al. 2008. 283:16279.
6. Hickey MJ, et al. 1993. Proc. Natl. Acad. Sci. 90:8327.
7. Shimomura T, et al. 1990. Blood. 75:2349.
8. Wu G, et al. 1997. Blood. 90:2660.

Gene ID
14729 View all products for this Gene ID
UniProt
View information about CD42d on UniProt.org

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