APC anti-mouse/rat CD42d Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1500	1

Product Details

Verified Reactivity

Mouse, Rat

Antibody Type

Monoclonal

Host Species

Armenian Hamster

Immunogen

Mouse platelets

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Red Laser (633 nm)

Application Notes

Additional reported applications (for relevant formats) include: immunoprecipitation^1,3.

Application References (PubMed link indicates BioLegend citation)

Takada K, et al. 1995. Hybridoma. 14:361. (IP)
Saito M, et al. 1996. Stem Cells. 14:124. (FC)
Sato N, et al. 2000. Hybridoma. 19:455. (IP)

Product Citations

Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
Misumi I et al. 2019. Cell Rep. 27(5):1387-1396 . PubMed
Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed

RRID

AB_2564601 (BioLegend Cat. No. 148505) AB_2564602 (BioLegend Cat. No. 148506)

Antigen Details

Structure: 83 kD heterodimer composed of 2 polypeptide chains, an α chain (GP1BA) and a β chain (GP1BB).
Distribution: Resting platelets and megakaryocytes.
Function: CD42d is a component of the GPIb-V-IX complex, functions as a vWF receptor, and mediates vWF-dependent platelet adhesion to blood vessels.
Ligand/Receptor: CD42d.
Cell Type: Platelets, Megakaryocytes
Biology Area: Cell Adhesion, Cell Biology, Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Sivaraman B, et al. 2011. Biomaterials. 32:5365.
2. Berger G, et al. 1996. Blood. 87:1385.
3. Ravanat C, et al. 1997. Blood. 89:3253.
4. Andrews RK, et al. 1998. Biochemistry. 37:638.
5. Inoue O, et al. 2008. 283:16279.
6. Hickey MJ, et al. 1993. Proc. Natl. Acad. Sci. 90:8327.
7. Shimomura T, et al. 1990. Blood. 75:2349.
8. Wu G, et al. 1997. Blood. 90:2660.
Gene ID: 14729 View all products for this Gene ID
UniProt: View information about CD42d on UniProt.org

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