PE anti-human CD131 Antibody
- 产品名称：
- PE anti-human CD131 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 306104
- 产品应用：
- 306104
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 2628 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human IL-3R β chain transfected COS cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting1,2?and immunoprecipitation2. The 1C1 antibody does not block binding of IL-3 and is a non-neutralizing antibody.
- Application References
(PubMed link indicates BioLegend citation) -
- Stomski F, et al. 1998. J. Biol. Chem. 273:1192. (WB)
- Stomski F, et al. 1999. Blood 94:1933. (IP WB)
- Mark A, et al. 2000. Mol. Cell 6:99.
- Product Citations
-
- Cravedi P, et al. 2014. J Am Soc Nephrol. 25:2003. PubMed
- RRID
- AB_2085808 (BioLegend Cat. No. 306104)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, associates with the α subunit of IL-3, IL-5, GM-CSF receptors, 95-120 kD
- Distribution
-
Low levels on monocytes, granulocytes, eosinophils, basophils, hematopoietic progenitors, endothelial cells
- Function
- Signal transducing molecule of IL-3, IL-5, GM-CSF receptors
- Ligand/Receptor
- IL-3, IL-5, GM-CSF
- Cell Type
- Basophils, Endothelial cells, Eosinophils, Granulocytes, Hematopoietic stem and progenitors, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Sun Q, et al. 1999. Blood 94:1943.
2. Woodcock J, et al. 1997. Blood 90:3005.
3. Lopez A, et al. 1991. J. Biol. Chem. 266:24741.
- Gene ID
- 1439 View all products for this Gene ID
- UniProt
- View information about CD131 on UniProt.org
