FITC anti-mouse CD1d (CD1.1, Ly-38) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1080	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemistical staining, and blocking function³.
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This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact the Regents of the University of California.

Application References (PubMed link indicates BioLegend citation)

Fischer K, et al. 2004. P. Natl. Acad. Sci. USA 101:10685. (Block)
Brozovic S, et al. 2004. Nat. Med. 10:535.
Brossay L, et al. 1997. J. Immunol.. 159:1216. (Block)
Jiang J, et al. 2012. PLoS One. 7:47487. PubMed

Product Citations

Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
Egenolf D, et al. 2011. J Pharmacol Toxicol Methods. 63:236. PubMed
Lehrke MJ, et al. 2021. Elife. 10:. PubMed
Zhang GL, et al. 2020. Matrix Biol. 93:25. PubMed
Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
Zamora-Chimal J, et al. 2017. Immunobiology. 222(2):454-462. PubMed

RRID

AB_1236546 (BioLegend Cat. No. 123507) AB_1236549 (BioLegend Cat. No. 123508)

Antigen Details

Structure: 48 kD glycoprotein, Ig superfamily
Distribution: leukocytes, dendritic cells, epithelial cells, thymocytes
Function: Antigen presentation
Ligand/Receptor: similar to MHC class I, associate with ?-microglobulin
Cell Type: Dendritic cells, Epithelial cells, Leukocytes, Thymocytes
Biology Area: Immunology, Innate Immunity
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Brudin N, et al. 1998. J. Immunol. 161:3271.
2. Amano M, et al. 1998. J. Immunol. 161:1710.
3. Brossay L, et al. 1997. J. Immunol. 159:1216.
4. Dougan SK, et al. 2007. Curr. Top. Microbiol. Immunol. 314:113.
5. Brutkiewicz RR, et al. 2007. Eur. J. Immunol. 37:2390.
Gene ID: 12479 View all products for this Gene ID
UniProt: View information about CD1d on UniProt.org

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