Purified anti-SPHK1 Antibody
- 产品名称：
- Purified anti-SPHK1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 658302
- 产品应用：
- 658302
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- SPHK1 peptide-KLH
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2562878 (BioLegend Cat. No. 658302)
- Structure
- 384-470 amino acids, predicted molecular weight of 45-60 kD.
- Distribution
-
Cytoplasm and nucleus.
- Function
- SPHK1 is a lipid kinase that catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate( S1P). It plays important roles in immunological, inflammatory diseases, and cancer.
- Interaction
- ACY1, calmodulin, and SPHKAP.
- Ligand/Receptor
- Sphingosine.
- Biology Area
- Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Protein Kinases/Phosphatase
- Antigen References
-
1. Wallington-Beddoe CT, et al. 2013. Br. J. Haematol. 161:623.
2. Hisano Y, et al. 2012. J. Biochem. 152:305.
3. Carr JM, et al. 2013. Rev. Med. Virol. 23:73.
4. Maceyka M, et al. 2012. Trends Cell Biol. 22:50.
5. Shida D, et al. 2008. Curr. Drug Targets. 9:662.
- Gene ID
- 8877 View all products for this Gene ID
- UniProt
- View information about SPHK1 on UniProt.org
