Purified anti-C2H2 zinc finger protein phospho lin-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4020	1

规格

价格

库存

100µg

￥ 4020

Product Details

Verified Reactivity: Mouse, Human
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g/ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: The antibody recognizes the mitotically-phosphorylated form of the HTGEKP conserved motif of C2H2 Zinc finger proteins. This is conserved across most higher eukaryotic species and is found in mitotic cells of human and mouse (and most eukaryotic) species.
RRID: AB_2616798 (BioLegend Cat. No. 685702)

Structure: Conserved linker region (HTGEKP) of C2H2 zinc finger proteins.
Distribution: Mitotic cells.
Function: The linker region (HTGEKP) of C2H2 zinc finger proteins facilitate stable DNA binding and is highly conserved among these zinc finger proteins. During mitosis, C2H2 zinc finger proteins are phosphorylated on the threonine residue of the linker peptide, which result in the inactivation of their DNA binding activity.
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Transcription Factors
Molecular Family: Phospho-Proteins
Antigen References: 1. Dovat S, et al. 2002. Genes Dev. 16:2985.
2. Rizkallah R, et al. 2011. Cell Cycle 10:3327.
3. Rizkallah R, et al. 2015. Oncotarget. 6:1446.
Gene ID: NA
UniProt: View information about C2H2 zinc finger proteins on UniProt.org