Ultra-LEAF™ Purified anti-human CD85g (ILT7)
- 产品名称：
- Ultra-LEAF™ Purified anti-human CD85g (ILT7)
- 产品类别：
- 抗体
- 产品编号：
- 326413
- 产品应用：
- 326413
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC -?Quality tested
FA -?Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported (for the relevant formats) applications include: trigger ILT7 mediated signaling.The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 326413 and 326414).
- Application References
(PubMed link indicates BioLegend citation) -
- Jensen MA, et al. 2013. Ann Rheum Dis. 72:596. PubMed.
- RRID
- AB_2860854 (BioLegend Cat. No. 326413) AB_2860855 (BioLegend Cat. No. 326414)
- Structure
- Associate with FcεR1γ leukocyte immunoglobulin-like receptor gene family
- Distribution
-
Plasmacytoid dendritic cells
- Function
- Negatively regulates pDC mediated innate immune function
- Cell Type
- Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Cao W, et al. 2006. J. Exp. Med. 203(6):1399.
2. Brown D, et al. 2004. Tissue Antigen. 64:215.
3. Rissoan MC, et al. 2002. Blood 100:3295.
- Gene ID
- 23547 View all products for this Gene ID
- UniProt
- View information about CD85 on UniProt.org
