Purified anti-mouse CLEC-2 (CLEC1B) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 2820	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

RBL-2H3 cells stably expressing HA-tagged mouse CLEC2.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for relevant formats) include: Western blotting¹.

Application References (PubMed link indicates BioLegend citation)

Mourpo-S? D, et al. 2011. Eur. J. Immunol. 41:3040. (WB)

Product Citations

Bergsma A, et al. 2019. Bone Rep. 10:100196. PubMed

RRID

AB_2562240 (BioLegend Cat. No. 146102)

Antigen Details

Structure: Type II transmembrane protein with a single cytoplasmic YXXL sequence known as a hem-immunoreceptor tyrosine-based activation motif (hemITAM)
Distribution: Platelets, megakaryocytes, granulocytes, monocytes, macrophages, and dendritic cells
Function: Involved in platelet aggregation and secretion as well as neutrophil phagocytosis
Ligand/Receptor: Venom toxin, rhodocytin, and podoplanin
Cell Type: Dendritic cells, Granulocytes, Macrophages, Megakaryocytes, Monocytes, Platelets, Neutrophils
Biology Area: Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References: 1. Boulaftali Y, et al. 2013. J. Clin. Invest. 123:908.?
2. Manne BK, et al. 2013. J. Biol. Chem. 288:7717.
3. Acton SE, et al. 2012. Immunity. 37:276.?
4. Finney BA, et al. 2012. Blood 119:1747.?
5. Kerrigan AM, et al. 2009. J. Immunol. 182:4150.
Gene ID: 56760 View all products for this Gene ID
UniProt: View information about CLEC-2 on UniProt.org

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