PE anti-mouse Trem-like 4 (Treml4) Antibody
- 产品名称：
- PE anti-mouse Trem-like 4 (Treml4) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 143303
- 产品应用：
- 143303
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Extracellular domain of recombinant mouse Trem-like 4
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunofluorescent staining, immunoprecipitation, and Western blotting1.
- Application References
(PubMed link indicates BioLegend citation) -
- Hemmi H, et al. 2009. J. Immunol. 182:1278. (WB)
- Product Citations
-
- Devalaraja S, et al. 2020. Cell. 1098:180. PubMed
- Pek RH, et al. 2019. Elife. 8:e49503. PubMed
- Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
- Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
- RRID
- AB_11126143 (BioLegend Cat. No. 143303) AB_11125372 (BioLegend Cat. No. 143304)
- Structure
- Type I transmembrane protein; member of the TREM family
- Distribution
-
CD8+ dendritic cells, dendritic cell subsets, macrophages in the spleen, myeloid cells
- Function
- Regulates innate immune response and homeostatis
- Interaction
- Associates with DAP12; binds late apoptotic cells/necrotic cells
- Cell Type
- B cells, Dendritic cells, Macrophages
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- MHC Antigens
- Antigen References
-
1. Ford JW and McVicar DW. 2009. Curr. Opin. Immunol. 21:38.
2. Hemmi H, et al. 2009. J. Immunol. 182:1278.
- Gene ID
- 224840 View all products for this Gene ID
- UniProt
- View information about Trem-like 4 on UniProt.org
