PE anti-mouse CD159a (NKG2A-上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1548	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

C57BL/6 mouse CD94/NKG2A transfected CHO cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. The availability of such diagnostic and therapeutic use licenses cannot be guaranteed from the University of California.

Application References (PubMed link indicates BioLegend citation)

McMahon CW, et al. 2002. J. Immunol. 169:1444. (FC)
Vance RE, et al. 2002. P. Natl. Acad. Sci. USA 99:868. (FC)

Product Citations

Li Y, et al. 2014. PLoS One. 9:86927. PubMed
Alvarez M, et al. 2020. Cancers (Basel). 12:. PubMed
Kissiov DU, et al. 2022. Elife. 11:. PubMed
Theurich S et al. 2017. Cell metabolism. 26(1):171-184 . PubMed
Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed

RRID

AB_10959654 (BioLegend Cat. No. 142803) AB_10965542 (BioLegend Cat. No. 142804)

Antigen Details

Structure: Type II transmembrane protein with extracelluar C-type lectin domains, complexed with CD94; 43 kD
Distribution: NK cells and NK T cells from C57BL/6 mouse
Function: Inhibitory activity via ITIMs
Ligand/Receptor: Non-classical MHC-I molecule Qa-1
Cell Type: Embryonic Stem Cells, Mesenchymal Stem Cells, NK cells, NKT cells
Biology Area: Cell Biology, Immunology, Signal Transduction, Stem Cells
Molecular Family: CD Molecules, MHC Antigens
Antigen References: 1. Vance RE, et al. 1998. J. Exp. Med. 188:1841.
2. Lohwasser S, et al. 1999. Eur. J. Immunol. 29:755.
3. Sivakumar PV, et al. 1999. J. Immunol. 162:6976.
4. Silver ET, et al. 1999. Immunogenetics 49:727.
5. Vance RE, et al. 1999. J. Exp. Med. 190:1801.
Gene ID: 16641 View all products for this Gene ID
UniProt: View information about CD159a on UniProt.org

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