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APC anti-mouse CD159a (NKG2A
产品名称:
APC anti-mouse CD159a (NKG2A
产品类别:
抗体
产品编号:
142807
产品应用:
142807
[价格]
规格 价格 库存
50µg ¥ 1572 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
C57BL/6 mouse CD94/NKG2A transfected CHO cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. The availability of such diagnostic and therapeutic use licenses cannot be guaranteed from the University of California.

Application References

(PubMed link indicates BioLegend citation)
  1. McMahon CW, et al. 2002. J. Immunol. 169:1444. (FC)
  2. Vance RE, et al. 2002. P. Natl. Acad. Sci. USA 99:868. (FC)
Product Citations
  1. Afolabi LO, et al. 2021. Front Immunol. 12:701671. PubMed
  2. Shreeve N, et al. 2021. Immunity. 54(6):1231-1244.e4. PubMed
RRID
AB_11125166 (BioLegend Cat. No. 142807) AB_11124538 (BioLegend Cat. No. 142808)

Antigen Details

Structure
Type II transmembrane protein with extracelluar C-type lectin domains, complexed with CD94; 43 kD
Distribution

NK cells and NK T cells from C57BL/6 mouse

Function
Inhibitory activity via ITIMs
Ligand/Receptor
Non-classical MHC-I molecule Qa-1
Cell Type
Embryonic Stem Cells, Mesenchymal Stem Cells, NK cells, NKT cells
Biology Area
Cell Biology, Immunology, Signal Transduction, Stem Cells
Molecular Family
CD Molecules, MHC Antigens
Antigen References

1. Vance RE, et al. 1998. J. Exp. Med. 188:1841.
2. Lohwasser S, et al. 1999. Eur. J. Immunol. 29:755.
3. Sivakumar PV, et al. 1999. J. Immunol. 162:6976.
4. Silver ET, et al. 1999. Immunogenetics 49:727.
5. Vance RE, et al. 1999. J. Exp. Med. 190:1801.

Gene ID
16641 View all products for this Gene ID
UniProt
View information about CD159a on UniProt.org

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