热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
Alexa Fluor® 647 anti-mouse/rat/human FOXP3 An
产品名称：
Alexa Fluor® 647 anti-mouse/rat/human FOXP3 An
产品类别：
抗体
产品编号：
320013
产品应用：
320013
[价格]
规格 价格 库存
25tests ￥ 2256 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Reported Reactivity
Cynomolgus, Rhesus, Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full-length FOXP3 protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The FOXP3 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear? Transcription Factor Staining Protocol. For flow cytometric staining, the suggested use of this reagent is 5 ?l per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser
Red Laser (633 nm)
Application Notes

NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.

Application References

(PubMed link indicates BioLegend citation)
  1. Roncador G, et al. 2005 Eur. J. Immunol. 35:1681.
  2. Mayack. S,et al. 2006. J. Immunol.176:2059. J. Immunol
  3. Yang ZZ, et al. 2006. Blood 107:3639.
  4. Gavin MA, et al. 2006. P. Natl. Acad. Sci. USA 103:6659.
  5. Groh V, et al. 2006. Nature Immunology 7:755.
  6. Lewkowicz P, et al. 2006 J. Immunol. 177:7155.
  7. Luke PPW, et al. 2006. Amer. J. Transplant. 6(9):2023.
  8. Bamias G, et al. 2007. J. Immunol. 178:1809.
  9. Valencia X, et al. 2007. J. Immunol. 178:2579.PubMed
  10. Davidson TS, et al. 2007. J. Immunol. 178:4022.
  11. MacDonald K PA, et al. 2007. Blood doi:10.1182/blood-2007-01-067249.
  12. Jaffar Z, et al. 2007. J. Immunol. 179:6193.
  13. Müller M, et al. 2007. J. Immunol. 179:2774.
  14. Jordan JM,et al. 2008.Infect Human. 76:3717. PubMed
  15. Golovina TN,et al. 2008. J. Immunol. 181:2855. PubMed
  16. Fallarino F, et al. 2009. J. Exp Med. 206:2511. PubMed
  17. Banham Alison, et al. 2009. Vet Immunol and Immunop 127.3-4:376-381
  18. Klunker S, et al. 2009. J. Exp Med. PubMed
  19. Haque A, et al. 2010. J. Immunol. 184:2583. PubMed
  20. Liu Y, et al. 2012. Food Chem Toxicol. 50:1920. PubMed
Product Citations
  1. Li S, et al. 2014. Virus Res. 180:84. PubMed
  2. Palacios-Arreola M, et al. 2017. Sci Rep. 10.1038/s41598-017-10135-1. PubMed
  3. Jayachandran R, et al. 2019. Immunity. 50:152. PubMed
  4. Gao R, et al. 2021. iScience. 24:103133. PubMed
  5. Chan JA, et al. 2022. Nat Commun. 13:4159. PubMed
  6. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  7. Hoang TN, et al. 2021. Cell. 184:460. PubMed
  8. Haque A, et al. 2010. J Immunol. 184:2583. PubMed
  9. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  10. Kuwahara M, et al. 2014. Nat Commun. 5:3555. PubMed
  11. Di Blasi D, et al. 2019. Cell Mol Gastroenterol Hepatol. 0.510416667. PubMed
  12. Aqel SI, et al. 2021. JCI Insight. 6:e142376. PubMed
  13. Alissafi T, et al. 2020. Cell Metabolism. 32(4):591-604.e7. PubMed
  14. Kim DH, et al. 2021. eLife. 10:00. PubMed
  15. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  16. Liu YJ, et al. 2020. Theranostics. 10:5225. PubMed
  17. Colleen S McGary et al. 2017. Immunity. 47(4):776-788 . PubMed
  18. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  19. Thauland T, et al. 2014. J Immunol. 193:5894. PubMed
  20. Bamias G, et al. 2007. J Immunol. 178:1809. PubMed
  21. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  22. Hoang TN, et al. 2020. bioRxiv. . PubMed
  23. Prosser A, et al. 2021. Cell Reports. 35(7):109141. PubMed
  24. Frazier T, et al. 2018. Adipocyte. 0.41875. PubMed
  25. Chen L, et al. 2021. Cell Death Differ. 28:1880. PubMed
  26. Ma W, et al. 2017. Sci Rep. . 10.1038/s41598-017-15661-6. PubMed
  27. Zhong W, et al. 2022. Nat Commun. 13:4390. PubMed
  28. Werbner M, et al. 2019. mSystems. 4:e00292-18. PubMed
  29. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  30. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  31. Harper JL, et al. 2020. Nat Med. 519:26. PubMed
  32. Pathania AS, et al. 2022. Mol Ther Oncolytics. 25:308. PubMed
  33. Wang Z, et al. 2015. Mol Oncol. 9: 1458-1470. PubMed
  34. He B, et al. 2020. Cell Reports. 30(3):714-724.e5.. PubMed
  35. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  36. Kato H, et al. 2021. Frontiers in Immunology. 12:635531. PubMed
  37. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  38. Abu-El-Rub E, et al. 2020. Cell Death Dis. 0.749305556. PubMed
  39. Toriyama K, et al. 2020. Commun Biol. 0.398611111. PubMed
  40. Gonzalez MM, et al. 2021. J Clin Invest. 131:. PubMed
  41. Chen Y, et al. 2021. Braz J Med Biol Res. 54:e9570. PubMed
  42. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
RRID
AB_439749 (BioLegend Cat. No. 320013) AB_439750 (BioLegend Cat. No. 320014)

Antigen Details

Structure
Forkhead/winged-helix transcription factor family, approximately 50 kD, contains zinc finger and forkhead domains
Distribution

Nuclear; expressed in T regulatory cells

Function
Transcription factor proposed to be a master regulatory gene in T regulatory cell development and a critical factor for immune homeostasis
Interaction
Interacts with DNA
Cell Type
Tregs
Biology Area
Cell Biology, Immunology, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Hori S, et al. 2003. Science 299:1057.

Regulation
FOXP3 is present at high levels in T regulatory cell can also be induced by T cell activation
Gene ID
20371 View all products for this Gene ID 317382 View all products for this Gene ID 50943 View all products for this Gene ID
UniProt
View information about FOXP3 on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线