热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
Purified anti-human CD206 (MMR) Antibody
产品名称：
Purified anti-human CD206 (MMR) Antibody
产品类别：
抗体
产品编号：
321101
产品应用：
321101
[价格]
规格 价格 库存
25µg ￥ 780 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified human mannose receptor
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
WB, ICC, IHC-F - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume or per 100 ?l whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting1, blocking of ligand binding1,2, immunofluorescence3, and immunohistochemical staining of acetone-fixed frozen tissue sections1. The Utra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 321149 and 321150).

Application References

(PubMed link indicates BioLegend citation)
  1. Noorman F, et al. 1997. J. Leukocyte Biol. 61:63. (WB, IHC, Block)
  2. Barrett-Bergshoeff M, et al. 1997. Thromb Haemost. 77:718. (Block)
  3. Kato M, et al. 2007. J. Immunol. 179:6052. (IF)
Product Citations
  1. Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
  2. Behrens NE, et al. 2019. MBio. 10:2. PubMed
  3. Laudanski K, et al. 2018. J Transl Med. 0.765972222. PubMed
  4. Camiolo MJ, et al. 2021. Cell Reports. 35(2):108974. PubMed
  5. Muir LA, et al. 2022. JCI Insight. 7:. PubMed
  6. Martin JC, et al. 2020. Cell. 178(6):1493-1508.e20.. PubMed
  7. Azari S, et al. 2021. MBio. 12:e0184921. PubMed
  8. Hu G, et al. 2021. Nat Commun. 12:773. PubMed
  9. Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
  10. Gardet A, et al. 2010. J Immunol. 185:5577. PubMed
  11. Brasil da Costa FH, et al. 2020. PLoS One. 15:e0230354. PubMed
  12. Correia CR, et al. 2017. Biomater Sci. 5:551. PubMed
  13. Lee SE, et al. 2021. JCI Insight. 6:. PubMed
  14. Li S, et al. 2019. Front Neurol. 1.036805556. PubMed
  15. De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed
  16. Cao H, et al. 2021. Nat Commun. 12:1792. PubMed
  17. Chevrier S, et al. 2021. Cell Reports Medicine. 2(1):100166. PubMed
  18. Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
  19. Trumpi K, et al. 2018. Oncotarget. 3. PubMed
  20. Kim SH, et al. 2020. Neoplasia. 1.3375. PubMed
  21. Lavin Y et al. 2017. Cell. 169(4):750-765 . PubMed
RRID
AB_571922 (BioLegend Cat. No. 321101) AB_571923 (BioLegend Cat. No. 321102)

Antigen Details

Structure
Type I membrane protein, Pattern Recognition Receptor (PRR) family, C-type lectin superfamily, 162-175 kD
Distribution

Macrophages, dendritic cells, hepatic and lymphatic endothelial cells

Function
Pathogen binding, facilitate phagocytosis and endocytosis, macrophage activation and antigen presentation
Ligand/Receptor
Mannose, fucose, N-acetyl glucosamine
Cell Type
Dendritic cells, Endothelial cells, Macrophages
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Mason D, et al. Eds. 2002. Leukocyte Typing VII. Oxford University Press. p303
2. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
3. Apostolopoulos V and McKenzie IF. 2001. Curr. Mol. Med. 1:469.
4. Le Cabec V, et al. 2005. J. Leukocyte Biol. 77:934.
5. Barrett-Bergshoeff M, et al. 1997. Thromb. Haemostatis 77:718.

Gene ID
4360 View all products for this Gene ID
UniProt
View information about CD206 on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线