Purified anti-BID Antibody
- 产品名称：
- Purified anti-BID Antibody
- 产品类别：
- 抗体
- 产品编号：
- 645001
- 产品应用：
- 645001
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant BID fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1-2 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Kang SJ, et al. 2002. Cell. Death Differ. 9:1115.
- Li H, et al. 1998. Cell 94:491.
- RRID
- AB_2063468 (BioLegend Cat. No. 645001)
- Structure
- A 22 kD protein, contains only BH3 domain, but not the BH1, Bh2 and BH4 found in other Bcl-2 family members. BID does not contain C-terminal hydrophobic region characteristic of membrane bound Bcl-2 family.
- Distribution
-
Cytoplasmic, inside mitochondria once activated.
- Function
- Activated by caspase 8 in response to Fas/TNF-R1 death receptor signals.
- Ligand/Receptor
- Caspase 8, BAK
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology
- Antigen References
-
1. Wang K, et al. 1996. Genes Dev. 10:2859
- Gene ID
- 637 View all products for this Gene ID
- UniProt
- View information about BID on UniProt.org
